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Gene Expression Data
Assay Details
Assay
Reference: J:293790 Lewis EMA, et al., Geminin is required for Hox gene regulation to pattern the developing limb. Dev Biol. 2020 Aug 1;464(1):11-23
Assay type: RNA in situ
MGI Accession ID: MGI:6694238
Gene symbol: Hoxd10
Gene name: homeobox D10
Probe: Hoxd10 probe7
Probe preparation: Antisense RNA
Results
Specimen 3 E11.25 cont: embryonic day 11.25; Gmnntm1c(KOMP)Wtsi/Gmnn+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: forelimb bud Present 3_Hoxd10-1 , 3_Hoxd10-2

Specimen 3 E11.25 mut: embryonic day 11.25; Gmnntm1c(KOMP)Wtsi/Gmnntm1c(KOMP)Wtsi, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: forelimb bud Present 3_Hoxd10-3 , 3_Hoxd10-4 Expression domain in mutant was expanded proximally, was more symmetric along the anteroposterior axis, and had less distinct borders than the control.

Specimen 3 E11.5 cont: embryonic day 11.5; Gmnntm1c(KOMP)Wtsi/Gmnn+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: forelimb bud Present 3_Hoxd10-5 , 3_Hoxd10-6

Specimen 3 E11.5 mut: embryonic day 11.5; Gmnntm1c(KOMP)Wtsi/Gmnntm1c(KOMP)Wtsi, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: forelimb bud Present 3_Hoxd10-7 , 3_Hoxd10-8 Expression domain in mutant was expanded proximally, was more symmetric along the anteroposterior axis, and had less distinct borders than the control.

Specimen 7 cont: embryonic day 11.5; Gmnntm1c(KOMP)Wtsi/Gmnn+, Twist2tm1(cre)Dor/Twist2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: hindlimb bud Present 7_Hoxd10-1 , 7_Hoxd10-2

Specimen 7 mut: embryonic day 11.5; Gmnntm1c(KOMP)Wtsi/Gmnntm1c(KOMP)Wtsi, Twist2tm1(cre)Dor/Twist2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: hindlimb bud Present 7_Hoxd10-4 , 7_Hoxd10-3 Similar as in the control.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory