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Gene Expression Data
Assay Details
Assay
Reference: J:293790 Lewis EMA, et al., Geminin is required for Hox gene regulation to pattern the developing limb. Dev Biol. 2020 Aug 1;464(1):11-23
Assay type: RNA in situ
MGI Accession ID: MGI:6694246
Gene symbol: Hoxd12
Gene name: homeobox D12
Probe: Hoxd12 probe17
Probe preparation: Antisense RNA
Results
Specimen 3 E11.25 cont: embryonic day 11.25; Gmnntm1c(KOMP)Wtsi/Gmnn+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: forelimb bud Present 3_Hoxd12-1 , 3_Hoxd12-2
Specimen 3 E11.25 mut: embryonic day 11.25; Gmnntm1c(KOMP)Wtsi/Gmnntm1c(KOMP)Wtsi, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: forelimb bud Present 3_Hoxd12-4 , 3_Hoxd12-3 Expression domain in mutant forelimb buds was expanded proximally and was more symmetric along the anteroposterior axis than the control.
Specimen 3 E11.5 cont: embryonic day 11.5; Gmnntm1c(KOMP)Wtsi/Gmnn+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: forelimb bud Present 3_Hoxd12-5 , 3_Hoxd12-6
Specimen 3 E11.5 mut: embryonic day 11.5; Gmnntm1c(KOMP)Wtsi/Gmnntm1c(KOMP)Wtsi, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: forelimb bud Present 3_Hoxd12-8 , 3_Hoxd12-7 Expression domain in mutant forelimb buds was expanded proximally and was more symmetric along the anteroposterior axis than the control.
Specimen 7 E11.5 cont: embryonic day 11.5; Gmnntm1c(KOMP)Wtsi/Gmnn+, Twist2tm1(cre)Dor/Twist2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: hindlimb bud Present 7_Hoxd12-2 , 7_Hoxd12-1
Specimen 7 E11.5 mut: embryonic day 11.5; Gmnntm1c(KOMP)Wtsi/Gmnntm1c(KOMP)Wtsi, Twist2tm1(cre)Dor/Twist2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: hindlimb bud Present 7_Hoxd12-4 , 7_Hoxd12-3 Similar as in the control.
Specimen 7 E12.5 cont: embryonic day 12.5; Gmnntm1c(KOMP)Wtsi/Gmnn+, Twist2tm1(cre)Dor/Twist2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: hindlimb Present 7_Hoxd12-5 , 7_Hoxd12-6
Specimen 7 E12.5 mut: embryonic day 12.5; Gmnntm1c(KOMP)Wtsi/Gmnntm1c(KOMP)Wtsi, Twist2tm1(cre)Dor/Twist2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: hindlimb Present 7_Hoxd12-8 , 7_Hoxd12-7 Mutant expression had expanded to the anterior boundary of the hindlimb bud.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/17/2024
MGI 6.24 		The Jackson Laboratory