Hoxd13 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:293790 Lewis EMA, et al., Geminin is required for Hox gene regulation to pattern the developing limb. Dev Biol. 2020 Aug 1;464(1):11-23
Assay type:	RNA in situ
MGI Accession ID:	MGI:6694247
Gene symbol:	Hoxd13
Gene name:	homeobox D13

Probe:	Hoxd13 probe38
Probe preparation:	Antisense RNA

Results

3_Hoxd13-1 ©

3_Hoxd13-2 ©

Specimen 3 cont: embryonic day 11.5; Gmnn^{tm1c(KOMP)Wtsi}/Gmnn⁺, Tg(Prrx1-cre)1Cjt/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS19: forelimb bud	Present		3_Hoxd13-2 , 3_Hoxd13-1

3_Hoxd13-3 ©

3_Hoxd13-4 ©

Specimen 3 mut: embryonic day 11.5; Gmnn^{tm1c(KOMP)Wtsi}/Gmnn^{tm1c(KOMP)Wtsi}, Tg(Prrx1-cre)1Cjt/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS19: forelimb bud	Present		3_Hoxd13-4 , 3_Hoxd13-3	Expression domain in mutant forelimb buds was expanded proximally versus control.

6C-1 ©

6C-2 ©

6C-3 ©

Specimen 6C cont: embryonic day 11.5; Gmnn^{tm1c(KOMP)Wtsi}/Gmnn⁺, Twist2^tm1(cre)Dor/Twist2⁺ (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS19: hindlimb bud	Present		6C-1 , 6C-3 , 6C-2

6C-4 ©

6C-5 ©

6C-6 ©

Specimen 6C mut: embryonic day 11.5; Gmnn^{tm1c(KOMP)Wtsi}/Gmnn^{tm1c(KOMP)Wtsi}, Twist2^tm1(cre)Dor/Twist2⁺ (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS19: hindlimb bud	Present		6C-6 , 6C-5 , 6C-4	Mutant had ectopic domain of expression in the anterior hindlimb bud at low penetrance (1/8 embryos assayed).

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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