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Gene Expression Data
Assay Details
Assay
Reference: J:293790 Lewis EMA, et al., Geminin is required for Hox gene regulation to pattern the developing limb. Dev Biol. 2020 Aug 1;464(1):11-23
Assay type: RNA in situ
MGI Accession ID: MGI:6694278
Gene symbol: Ptch1
Gene name: patched 1
Probe: Ptch1 probe25
Probe preparation: Antisense RNA
Results
Specimen 4 cont: embryonic day 11.5; Gmnntm1c(KOMP)Wtsi/Gmnn+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: forelimb bud Present 4_Ptch1-1 , 4_Ptch1-2
Specimen 4 mut: embryonic day 11.5; Gmnntm1c(KOMP)Wtsi/Gmnntm1c(KOMP)Wtsi, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: forelimb bud Present 4_Ptch1-4 , 4_Ptch1-3 Expression domain in mutant forelimb buds was expanded anteriorly versus control.
Specimen 6B cont: embryonic day 11.5; Gmnntm1c(KOMP)Wtsi/Gmnn+, Twist2tm1(cre)Dor/Twist2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: hindlimb bud Present 6B-1 , 6B-2 , 6B-3
Specimen 6B mut: embryonic day 11.5; Gmnntm1c(KOMP)Wtsi/Gmnntm1c(KOMP)Wtsi, Twist2tm1(cre)Dor/Twist2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: hindlimb bud Present 6B-5 , 6B-4 , 6B-6 Mutant had ectopic domain of expression in the anterior hindlimb bud with partial penetrance (3/4 embryos assayed).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
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