Gene Expression Data
Assay Details
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Assay
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Reference:
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J:297547
Leca I, et al., A proteomic survey of microtubule-associated proteins in a R402H TUBA1A mutant mouse. PLoS Genet. 2020 Nov;16(11):e1009104
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6695141
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Gene symbol:
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Foxp2
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Gene name:
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forkhead box P2
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Antibody:
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anti-FOXP2 (ab16046)
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Detection system:
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Secondary antibody coupled to Alexa Fluor
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Assay notes:
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Specimens were subjected to heat-mediated antigen retrieval.
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Results
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Specimen
1P:
postnatal week 8-10; Emx1tm1(cre)Krj/Emx1 +
(more  )
Note: coronal section
Specimen
1P:
(close  )
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Genetic Background:
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involves: 129S2/SvPas * C57BL/6J
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Mutant Allele(s):
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Emx1tm1(cre)Krj/Emx1+
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Age:
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postnatal week 8-10
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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coronal section
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Specimen
1Q:
postnatal week 8-10; Tuba1atm1.1Dak/Tuba1a +
(more )
Note: coronal section
Specimen
1Q:
(close )
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Genetic Background:
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involves: 129S2/SvPas * C57BL/6J
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Mutant Allele(s):
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Tuba1atm1.1Dak/Tuba1a+
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Age:
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postnatal week 8-10
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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coronal section
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Specimen
1R:
(close )
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Genetic Background:
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involves: 129S2/SvPas * C57BL/6J
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Mutant Allele(s):
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Tuba1atm1.1Dak/Tuba1a+
Emx1tm1(cre)Krj/Emx1+
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Age:
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postnatal week 8-10
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Conditional mutant. coronal section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cortical layer VI |
Present |
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1R
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Expression is present in neurons. In the mutant the number of expressing cells is comparable to that in the controls but the layer is less defined (ie the neurons are more widely distributed).
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Analysis Tools