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Gene Expression Data
Assay Details
Assay
Reference: J:294646 Stupnikov MR, et al., Jagged and Delta-like ligands control distinct events during airway progenitor cell differentiation. Elife. 2019 Oct 21;8:e50487
Assay type: RNA in situ
MGI Accession ID: MGI:6695184
Gene symbol: Upk3a
Gene name: uroplakin 3A
Probe: Upk3a probe2
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 3F control: embryonic day 18.5 (more )
Note: Double labeled: blue - Upk3a; brown - Ascl1 (assay MGI:6695186).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present 3F upper left , 3F upper right Expressed predominantly in secretory precursors tightly associated with the developing neuroepithelial bodies and signals scattered elsewhere.
Specimen 3F Jag1/2 cnull: embryonic day 18.5; Jag1tm1Jlew/Jag1tm1Jlew, Jag2tm2.1Grid/Jag2tm2.1Grid, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: blue - Upk3a; brown - Ascl1 (assay MGI:6695186).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present Clusters 3F lower left , 3F lower right Expression was restricted to secretory precursors surrounding the developing neuroepithelial bodies.
Specimen 6B control: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present Regionally restricted 6B left Expressed predominantly in secretory precursors tightly associated with the developing neuroepithelial bodies.
Specimen 6B Dll1/4 cnull: embryonic day 18.5; Dll1tm1Mjo/Dll1tm1Mjo, Dll4tm1Frad/Dll4tm1Frad, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present Regionally restricted 6B right Marked expansion of the expression domain in intrapulmonary airways, compared with the control.
Specimen 6C control: embryonic day 18.5 (more )
Note: Double labeled: blue - Upk3a; brown - Ascl1 (assay MGI:6695186).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present Regionally restricted 6C left Expressed in secretory precursors tightly associated with the developing neuroepithelial body.
Specimen 6C Dll1/4 cnull: embryonic day 18.5; Dll1tm1Mjo/Dll1tm1Mjo, Dll4tm1Frad/Dll4tm1Frad, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: blue - Upk3a; brown - Ascl1 (assay MGI:6695186).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present Regionally restricted 6C right Marked expansion of the expression domain associated with the neuroepithelial body, compared with the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory