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Gene Expression Data
Assay Details
Assay
Reference: J:294646 Stupnikov MR, et al., Jagged and Delta-like ligands control distinct events during airway progenitor cell differentiation. Elife. 2019 Oct 21;8:e50487
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6695186
Gene symbol: Ascl1
Gene name: achaete-scute family bHLH transcription factor 1
Antibody: anti-MASH (24B72D11), eBioscience
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 3F control: embryonic day 18.5 (more )
Note: Double labeled: brown - Ascl1; blue - Upk3a (assay MGI:6695184).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present Clusters 3F upper right Expressed in epithelial cell clusters at sites of neuroepithelial bodies formation.
Specimen 3F Jag1/2 cnull: embryonic day 18.5; Jag1tm1Jlew/Jag1tm1Jlew, Jag2tm2.1Grid/Jag2tm2.1Grid, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: brown - Ascl1; blue - Upk3a (assay MGI:6695184).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present Clusters 3F lower right Expressed in epithelial cell clusters at sites of neuroepithelial bodies formation.
Specimen 5B control: embryonic day 18.5 (more )
Note: Double labeled: brown - Ascl1; purple - Cyp2f2 (assay MGI:6695197).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present Clusters 5B left Expressed in epithelial cell clusters at sites of neuroepithelial bodies formation.
Specimen 5B Dll1/4 cnull: embryonic day 18.5; Dll1tm1Mjo/Dll1tm1Mjo, Dll4tm1Frad/Dll4tm1Frad, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: brown - Ascl1; purple - Cyp2f2 (assay MGI:6695197).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present 5B right Abnormally expanded in the population of positive cells compared with the control.
Specimen 6C control: embryonic day 18.5 (more )
Note: Double labeled: brown - Ascl1; blue - Upk3a (assay MGI:6695184).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present Clusters 6C left Expressed in epithelial cell clusters at sites of neuroepithelial bodies formation.
Specimen 6C Dll1/4 cnull: embryonic day 18.5; Dll1tm1Mjo/Dll1tm1Mjo, Dll4tm1Frad/Dll4tm1Frad, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: brown - Ascl1; blue - Upk3a (assay MGI:6695184).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present Clusters 6C right An expansion in the population of positive cells compared with the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
MGI 6.24 		The Jackson Laboratory