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Gene Expression Data
Assay Details
Assay
Reference: J:294646 Stupnikov MR, et al., Jagged and Delta-like ligands control distinct events during airway progenitor cell differentiation. Elife. 2019 Oct 21;8:e50487
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6695196
Gene symbol: Notch1
Gene name: notch 1
Antibody: anti-Cleaved Notch1 (Val1744) (D3B8) (#4147)
Detection system: Secondary antibody
Results
Specimen 5A control: embryonic day 18.5 (more )
Note: Double labeled: red - Notch1; green - Ascl1 (assay MGI:6695189).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present Regionally restricted 5A control upper Expressed in secretory precursors tightly associated with the developing neuroepithelial bodies.
Specimen 5A Dll1/4 cnull: embryonic day 18.5; Dll1tm1Mjo/Dll1tm1Mjo, Dll4tm1Frad/Dll4tm1Frad, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: red - Notch1; green - Ascl1 (assay MGI:6695189).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present Regionally restricted 5A cKO upper Expressed in secretory precursors tightly associated with the developing neuroepithelial bodies, indistinguishable from controls.
Specimen 5A control-2: embryonic day 18.5 (more )
Note: Double labeled: red - Notch1; green - Fut4 (assay MGI:6695155).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Strong Regionally restricted 5A control middle Expressed in secretory precursors tightly associated with the developing neuroepithelial bodies.
Specimen 5A Dll1/4 cnull-2: embryonic day 18.5; Dll1tm1Mjo/Dll1tm1Mjo, Dll4tm1Frad/Dll4tm1Frad, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: red - Notch1; green - Fut4 (assay MGI:6695155).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Strong Regionally restricted 5A cKO middle Expressed in secretory precursors tightly associated with the developing neuroepithelial bodies, indistinguishable from controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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08/21/2024
MGI 6.24 		The Jackson Laboratory