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Gene Expression Data
Assay Details
Assay
Reference: J:216142 Amann R, et al., The FgfrL1 receptor is required for development of slow muscle fibers. Dev Biol. 2014 Oct 15;394(2):228-41
Assay type: RNA in situ
MGI Accession ID: MGI:6753251
Gene symbol: Myh7
Gene name: myosin, heavy polypeptide 7, cardiac muscle, beta
Probe: Myh7 cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4 wt: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: diaphragm dome Strong Regionally restricted 4_Myh7-2 , 4_Myh7-1 Expressed in slow muscle fibers (every third muscle fiber), yielding a zebra-like pattern.
TS26: crus of diaphragm Strong Regionally restricted 4_Myh7-1 Expressed in slow muscle fibers (every third muscle fiber), yielding a zebra-like pattern.
TS26: intercostal muscle Strong Regionally restricted 4_Myh7-1 Expressed in slow muscle fibers (every third muscle fiber), yielding a zebra-like pattern.
Specimen 4 ko: embryonic day 18.5; Fgfrl1tm1True/Fgfrl1tm1True (more )
Structure Level Pattern Image Note
TS26: intercostal muscle Present 4_Myh7-4
TS26: diaphragm dome Trace 4_Myh7-4 , 4_Myh7-3 Staining was extremely weak, only occasional, faintly positive fibers.
Specimen 5 E10.5 wt: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: somite Present 5_upper left
Specimen 5 E10.5 ko: embryonic day 10.5; Fgfrl1tm1True/Fgfrl1tm1True (more )
Structure Level Pattern Image Note
TS17: somite Present 5_upper right Similar as in the wild-type.
Specimen 5 E15.5 wt: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: diaphragm dome Present 5_lower left
TS23: intercostal muscle Present 5_lower left
Specimen 5 E15.5 ko: embryonic day 15.5; Fgfrl1tm1True/Fgfrl1tm1True (more )
Structure Level Pattern Image Note
TS23: diaphragm dome Present 5_lower right Similar as in the wild-type.
TS23: intercostal muscle Present 5_lower right Similar as in the wild-type.
Specimen 11A wt: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: diaphragm dome Present 11A Myh7-1 , 11A Myh7-2 Expressed in slow muscle fibers.
TS26: crus of diaphragm Present 11A Myh7-1 Expressed in slow muscle fibers.
TS26: intercostal muscle Present 11A Myh7-1 Expressed in slow muscle fibers.
Specimen 11A ko: embryonic day 18.5; Wnt4tm1Amc/Wnt4tm1Amc (more )
Structure Level Pattern Image Note
TS26: diaphragm dome Present 11A Myh7-3 , 11A Myh7-4 Expressed in slow muscle fibers, similar as in the wild-type.
TS26: crus of diaphragm Present 11A Myh7-4 Expressed in slow muscle fibers, similar as in the wild-type.
TS26: intercostal muscle Present 11A Myh7-4 Expressed in slow muscle fibers, similar as in the wild-type.
Specimen not shown: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: somite Present
Specimen not shown: embryonic day 11.5; Fgfrl1tm1True/Fgfrl1tm1True (more )
Structure Level Pattern Image Note
TS19: somite Present Similar as in the wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/29/2024
MGI 6.24 		The Jackson Laboratory