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Gene Expression Data
Assay Details
Assay
Reference: J:216142 Amann R, et al., The FgfrL1 receptor is required for development of slow muscle fibers. Dev Biol. 2014 Oct 15;394(2):228-41
Assay type: RNA in situ
MGI Accession ID: MGI:6753255
Gene symbol: Myl3
Gene name: myosin, light polypeptide 3
Probe: Myl3 cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4 wt: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: diaphragm dome Present Regionally restricted 4_Myl3-1 , 4_Myl3-2 Expressed in slow muscles in approximately 30% of all muscle fibers.
TS26: crus of diaphragm Present Regionally restricted 4_Myl3-1 Expressed in slow muscles in approximately 30% of all muscle fibers.
TS26: intercostal muscle Present Regionally restricted 4_Myl3-1 Expressed in slow muscles in approximately 30% of all muscle fibers.
Specimen 4 ko: embryonic day 18.5; Fgfrl1tm1True/Fgfrl1tm1True (more )
Structure Level Pattern Image Note
TS26: diaphragm dome Absent 4_Myl3-3 , 4_Myl3-4
Specimen 11A wt: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: diaphragm dome Present 11A Myl3-1 , 11A Myl3-2 Expressed in slow muscle fibers.
TS26: crus of diaphragm Present 11A Myl3-1 Expressed in slow muscle fibers.
TS26: intercostal muscle Present 11A Myl3-1 Expressed in slow muscle fibers.
Specimen 11A ko: embryonic day 18.5; Wnt4tm1Amc/Wnt4tm1Amc (more )
Structure Level Pattern Image Note
TS26: diaphragm dome Present 11A Myl3-4 , 11A Myl3-3 Expressed in slow muscle fibers, similar as in the wild-type.
TS26: crus of diaphragm Present 11A Myl3-4 Expressed in slow muscle fibers, similar as in the wild-type.
TS26: intercostal muscle Present 11A Myl3-4 Expressed in slow muscle fibers, similar as in the wild-type.
Specimen not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: somite Present
Specimen not shown: embryonic day 10.5; Fgfrl1tm1True/Fgfrl1tm1True (more )
Structure Level Pattern Image Note
TS17: somite Present Similar as in the wild-type.
Specimen not shown: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: somite Present
Specimen not shown: embryonic day 11.5; Fgfrl1tm1True/Fgfrl1tm1True (more )
Structure Level Pattern Image Note
TS19: somite Present Similar as in the wild-type.
Specimen not shown: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: diaphragm dome Present
TS23: intercostal muscle Present
Specimen not shown: embryonic day 15.5; Fgfrl1tm1True/Fgfrl1tm1True (more )
Structure Level Pattern Image Note
TS23: diaphragm dome Present Similar as in the wild-type.
TS23: intercostal muscle Present Similar as in the wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/29/2024
MGI 6.24 		The Jackson Laboratory