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Gene Expression Data
Assay Details
Assay
Reference: J:308708 Martinez ME, et al., The Type 3 Deiodinase Is a Critical Modulator of Thyroid Hormone Sensitivity in the Fetal Brain. Front Neurosci. 2021;15:703730
Assay type: RT-PCR
MGI Accession ID: MGI:6842448
Gene symbol: Dio3
Gene name: deiodinase, iodothyronine type III
Probe: Dio3-pK, Dio3-pL
Probe preparation: labelled with SYBR green
Assay notes: Quantitative RT-PCR was used to obtain these results. The housekeeping genes Gapdh or Rn18s were used to normalize expression levels.
Results
Image: 4E Dio3 ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex
+/+ E18.5 TS26: brain Present 1 µg; total RNA C57BL/6 Pooled
-/- E18.5 TS26: brain Present (a) 1 µg; total RNA B6.129-Dio3tm1Stg Dio3tm1Stg/Dio3tm1StgPooled
Notes:
(a) Expression levels are significantly upregulated in the mutant. (Although the message is transcribed in the mutant, due to point mutations, the protein is inactive.)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
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