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Gene Expression Data
Assay Details
Assay
Reference: J:243650 Herriges MJ, et al., The NANCI-Nkx2.1 gene duplex buffers Nkx2.1 expression to maintain lung development and homeostasis. Genes Dev. 2017 May 01;31(9):889-903
Assay type: RT-PCR
MGI Accession ID: MGI:6860399
Gene symbol: Nkx2-1
Gene name: NK2 homeobox 1
Probe: Nkx2.1-pA, Nkx2.1-pB
Probe preparation: labelled with SYBR green
Results
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex
Wild-type E12.5 TS20: forebrain Present Not Specified; total RNA Not Specified Not Specified
NANCIcreERT2-RFP/+ E12.5 TS20: forebrain Present (a) Not Specified; total RNA Not Specified Sfta3tm1.1(cre/ERT2)Eem/Sfta3+Not Specified
NANCIcreERT2-RFP/creERT2-RFP E12.5 TS20: forebrain Present (b) Not Specified; total RNA Not Specified Sfta3tm1.1(cre/ERT2)Eem/Sfta3tm1.1(cre/ERT2)EemNot Specified
Nkx2.1GFP/+ E12.5 TS20: forebrain Present (b) Not Specified; total RNA involves: 129S6/SvEvTac Nkx2-1tm1Ikono/Nkx2-1+Not Specified
NANCIcreERT2-RFP/+; Nkx2.1GFP/+ E12.5 TS20: forebrain Present (b) Not Specified; total RNA involves: 129S6/SvEvTac Nkx2-1tm1Ikono/Nkx2-1+, Sfta3tm1.1(cre/ERT2)Eem/Sfta3+Not Specified
Wild-type E18.5 TS26: forebrain Present Not Specified; total RNA Not Specified Not Specified
NANCIcreERT2-RFP/+ E18.5 TS26: forebrain Present (a) Not Specified; total RNA Not Specified Sfta3tm1.1(cre/ERT2)Eem/Sfta3+Not Specified
NANCIcreERT2-RFP/creERT2-RFP E18.5 TS26: forebrain Present (c) Not Specified; total RNA Not Specified Sfta3tm1.1(cre/ERT2)Eem/Sfta3tm1.1(cre/ERT2)EemNot Specified
Nkx2.1GFP/+ E18.5 TS26: forebrain Present (b) Not Specified; total RNA involves: 129S6/SvEvTac Nkx2-1tm1Ikono/Nkx2-1+Not Specified
NANCIcreERT2-RFP/+; Nkx2.1GFP/+ E18.5 TS26: forebrain Present (b) Not Specified; total RNA involves: 129S6/SvEvTac Nkx2-1tm1Ikono/Nkx2-1+, Sfta3tm1.1(cre/ERT2)Eem/Sfta3+Not Specified
Notes:
(a) Expression levels are comparable to those seen in wild type.
(b) Expression levels are reduced in this mutant.
(c) Unlike earlier in development, expression levels are comparable to those seen in wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
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