Ctnnb1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:308883 Karpinska K, et al., Alpha-Catulin, a New Player in a Rho Dependent Apical Constriction That Contributes to the Mouse Neural Tube Closure. Front Cell Dev Biol. 2020;8:154
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6887766
Gene symbol:	Ctnnb1
Gene name:	catenin beta 1

Antibody:	anti-Beta-catenin (C2206)
Detection system:	Secondary antibody coupled to Alexa Fluor 488

Results

2I ©

2I' ©

Specimen 2I: embryonic day 10.5 (more

)
Note: Double labeled: green - Ctnnb1; red - Nefm (assay MGI:6887767).

Structure	Level	Pattern	Image	Note
TS17: hindbrain	Present	Regionally restricted	2I , 2I'	Expression is in adherens junctions.

2J ©

2J' ©

Specimen 2J: embryonic day 10.5; Ctnnal1^{Gt(RRJ603)Byg}/Ctnnal1^{Gt(RRJ603)Byg} (more

)
Note: Double labeled: green - Ctnnb1; red - Nefm (assay MGI:6887767).

Structure	Level	Pattern	Image	Note
TS17: hindbrain	Present	Regionally restricted	2J , 2J'	Expression in this mutant indicates that the cells are loosely connected and separating. There is staining at the membranes, with disorganized cell-cell junctions with less elongated cells and more rounded nuclei.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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