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Gene Expression Data
Assay Details
Assay
Reference: J:220523 Harris JA, et al., Anatomical characterization of Cre driver mice for neural circuit mapping and manipulation. Front Neural Circuits. 2014;8:76
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7255041
Gene symbol: Chat
Gene name: choline O-acetyltransferase
Reporter: Cre
Probe: Cre probe 1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Horseradish peroxidase
Results
Specimen 1B: postnatal day 57; Chattm1(cre)Lowl/Chat+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: brain cholinergic neuron Present 1B ISH: Cre
Specimen Supp Table 1: postnatal day 28-58; Chattm1(cre)Lowl/Chat+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. The authors used more than one reporter allele to compile these data.
Structure Cell Type Level Pattern Image Note
TS28: medulla oblongata cholinergic neuron Present Regionally restricted
TS28: midbrain cholinergic neuron Present Regionally restricted
TS28: pons cholinergic neuron Present Regionally restricted
TS28: thalamus cholinergic neuron Present Regionally restricted
TS28: basal forebrain cholinergic neuron Present Scattered
TS28: corpus striatum cholinergic neuron Present Scattered
TS28: cerebral cortex cholinergic neuron Present Regionally restricted Expression in the cortex is sparce.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/17/2024
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