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Gene Expression Data
Assay Details
Assay
Reference: J:218166 Zhulyn O, et al., Ptch2 shares overlapping functions with Ptch1 in Smo regulation and limb development. Dev Biol. 2015 Jan 15;397(2):191-202
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7256485
Gene symbol: Ptch1
Gene name: patched 1
Reporter: lacZ
Direct Detection
Results
Specimen 3A: embryonic day 11.0; Ptch1tm1Mps/Ptch1+ (more )
Structure Level Pattern Image Note
TS18: forelimb bud mesenchyme Present Regionally restricted 3A Expression in posterior mesenchyme.
Specimen 3A': embryonic day 11.0; Ptch1tm1Mps/Ptch1+ (more )
Structure Level Pattern Image Note
TS18: forelimb bud apical ectodermal ridge Present Regionally restricted 3A' Authors report expression in posterior apical ectodermal ridge.
Specimen 3C: embryonic day 12.5; Ptch1tm1Mps/Ptch1+ (more )
Structure Level Pattern Image Note
TS20: hand mesenchyme Present Regionally restricted 3C Expression in posterior mesenchyme.
Specimen 3C': embryonic day 12.5; Ptch1tm1Mps/Ptch1+ (more )
Structure Level Pattern Image Note
TS20: hand epithelium Present Regionally restricted 3C' Expression in posterior apical ectodermal ridge (AER).
Specimen 3E: embryonic day 14.5; Ptch1tm1Mps/Ptch1+ (more )
Structure Level Pattern Image Note
TS22: hand mesenchyme Present 3E
Specimen S4E: embryonic day 12.5; Ptch1tm1Bjw/Ptch1tm1Mps (more )
Structure Level Pattern Image Note
TS20: limb Present S4E
TS20: trunk mesenchyme Present S4E
Specimen S4F: embryonic day 12.5; Ptch1tm1Bjw/Ptch1tm1Mps, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: limb Present S4F
TS20: trunk mesenchyme Present S4F
Specimen S5A: embryonic day 11.5; Ptch1tm1Mps/Ptch1+ (more )
Structure Level Pattern Image Note
TS19: apical ectodermal ridge Present Regionally restricted S5A Expression in the posterior apical ectodermal ridge (AER).
Specimen S5A': embryonic day 12.5; Ptch1tm1Mps/Ptch1+ (more )
Structure Level Pattern Image Note
TS20: hand epithelium Present Regionally restricted S5A' Expression in the posterior apical ectodermal ridge (AER).
Specimen S5B: embryonic day 11.5; Ptch1tm1Bjw/Ptch1tm1Mps, Tg(Msx2-cre)5Rem/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: apical ectodermal ridge Present Regionally restricted S5B Ectopic expression in anterior apical ectodermal ridge (AER).
Specimen S2B': embryonic day 12.5; Ptch1tm1Bjw/Ptch1tm1Mps, Tg(Msx2-cre)5Rem/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: hand epithelium Present Regionally restricted S5B' Ectopic expression in anterior apical ectodermal ridge (AER).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/24/2024
MGI 6.24 		The Jackson Laboratory