About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:218166 Zhulyn O, et al., Ptch2 shares overlapping functions with Ptch1 in Smo regulation and limb development. Dev Biol. 2015 Jan 15;397(2):191-202
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7256486
Gene symbol: Ptch2
Gene name: patched 2
Reporter: lacZ
Direct Detection
Results
Specimen 3B: embryonic day 11.0; Ptch2tm1Bjw/Ptch2+ (more )
Structure Level Pattern Image Note
TS18: forelimb bud mesenchyme Present Regionally restricted 3B Expression in posterior mesenchyme.
Specimen 3B': embryonic day 11.0; Ptch2tm1Bjw/Ptch2+ (more )
Structure Level Pattern Image Note
TS18: forelimb bud apical ectodermal ridge Present Regionally restricted 3B' Authors report expression in posterior apical ectodermal ridge.
Specimen 3D: embryonic day 12.5; Ptch2tm1Bjw/Ptch2+ (more )
Structure Level Pattern Image Note
TS20: hand mesenchyme Present Regionally restricted 3D Expression in posterior mesenchyme.
Specimen 3D': embryonic day 12.5; Ptch2tm1Bjw/Ptch2+ (more )
Structure Level Pattern Image Note
TS20: hand epithelium Present Regionally restricted 3D' Authors report expression in posterior apical ectodermal ridge.
Specimen 3F: embryonic day 14.5; Ptch2tm1Bjw/Ptch2+ (more )
Structure Level Pattern Image Note
TS22: hand Present 3F
Specimen S4B: embryonic day 12.5; Ptch2tm1Bjw/Ptch2+ (more )
Structure Level Pattern Image Note
TS20: limb mesenchyme Present Regionally restricted S4B Expression in posterior mesenchyme.
TS20: limb epithelium Present S4B Expression in ectoderm of limb.
TS20: vibrissa Present S4B
TS20: brain Present S4B
TS20: spinal cord Present S4B
Specimen S4C: embryonic day 12.5; Ptch2tm1Bjw/Ptch2tm1Bjw (more )
Structure Level Pattern Image Note
TS20: limb mesenchyme Present Regionally restricted S4C Expression in posterior mesenchyme.
TS20: limb epithelium Present S4C Expression in ectoderm of limb.
TS20: vibrissa Present S4C
TS20: brain Present S4C
TS20: spinal cord Present S4C
Specimen S5C: embryonic day 11.5; Ptch2tm1Bjw/Ptch2+ (more )
Structure Level Pattern Image Note
TS19: apical ectodermal ridge Present Regionally restricted S5C No expression in anterior apical ectodermal ridge (AER).
Specimen S5C': embryonic day 12.5; Ptch2tm1Bjw/Ptch2+ (more )
Structure Level Pattern Image Note
TS20: limb epithelium Present Regionally restricted S5C' No expression in the anterior apical ectodermal ridge (AER).
Specimen S5D: embryonic day 11.5; Ptch1tm1Bjw/Ptch1tm1Mps, Ptch2tm1Bjw/Ptch2+, Tg(Msx2-cre)5Rem/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: apical ectodermal ridge Present Regionally restricted S5D Ectopic expression in anterior apical ectodermal ridge (AER).
Specimen S5D': embryonic day 12.5; Ptch1tm1Bjw/Ptch1tm1Mps, Ptch2tm1Bjw/Ptch2+, Tg(Msx2-cre)5Rem/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: limb epithelium Present Regionally restricted S5D' Ectopic expression in anterior apical ectodermal ridge (AER).
Specimen 5M: embryonic day 12.5; Ptch2tm1Bjw/Ptch2+ (more )
Structure Level Pattern Image Note
TS20: limb epithelium Present Regionally restricted 5M No expression in anterior apical ectodermal ridge (AER).
Specimen 5M': embryonic day 12.5; Ptch1tm1Bjw/Ptch1tm1Mps, Ptch2tm1Bjw/Ptch2+, Tg(Msx2-cre)5Rem/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: limb epithelium Present Regionally restricted 5M' Ectopic expression in anterior apical ectodermal ridge (AER).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory