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Gene Expression Data
Assay Details
Assay
Reference: J:218166 Zhulyn O, et al., Ptch2 shares overlapping functions with Ptch1 in Smo regulation and limb development. Dev Biol. 2015 Jan 15;397(2):191-202
Assay type: RNA in situ
MGI Accession ID: MGI:7256490
Gene symbol: Fgf8
Gene name: fibroblast growth factor 8
Probe: Fgf8 probe125
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 4A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: apical ectodermal ridge Present 4A
Specimen 4B: embryonic day 11.5; Ptch1tm1Bjw/Ptch1tm1.1Bjw, Tg(Msx2-cre)5Rem/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: apical ectodermal ridge Present 4B No changes in expression compared with wildtype.
Specimen 4C: embryonic day 11.5; Ptch1tm1Bjw/Ptch1tm1Mps, Ptch2tm1Bjw/Ptch2tm1Bjw, Tg(Msx2-cre)5Rem/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: apical ectodermal ridge Present 4C No changes in expression compared with wildtype.
Specimen 7H: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS16: apical ectodermal ridge Present 7H
Specimen 7J: embryonic day 10.5; Ptch1tm1Bjw/Ptch1tm1.1Bjw, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS16: apical ectodermal ridge Absent 7J Loss of expression in apical ectodermal ridge.
Specimen 7L: embryonic day 10.5; Ptch1tm1Bjw/Ptch1tm1.1Bjw, Ptch2tm1Hui/Ptch2tm1Hui, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS16: apical ectodermal ridge Absent 7L Loss of expression in apical ectodermal ridge.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
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