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Gene Expression Data
Assay Details
Assay
Reference: J:218166 Zhulyn O, et al., Ptch2 shares overlapping functions with Ptch1 in Smo regulation and limb development. Dev Biol. 2015 Jan 15;397(2):191-202
Assay type: RNA in situ
MGI Accession ID: MGI:7256491
Gene symbol: Grem1
Gene name: gremlin 1, DAN family BMP antagonist
Probe: Grem1 probe14
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 4G: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: limb bud Present 4G
Specimen 4H: embryonic day 11.5; Ptch1tm1Bjw/Ptch1tm1.1Bjw, Tg(Msx2-cre)5Rem/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: limb bud Present Regionally restricted 4H Ectopic expression in anterior of limb upon loss of Ptch1.
Specimen 4I: embryonic day 11.5; Ptch1tm1Bjw/Ptch1tm1Mps, Ptch2tm1Bjw/Ptch2tm1Bjw, Tg(Msx2-cre)5Rem/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: limb bud Present Regionally restricted 4I Ectopic expression in anterior of limb further exacerbated upon loss of both Ptch1 and Ptch2.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
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