|
Results
|
Specimen
2A:
(close  )
|
Genetic Background:
|
involves: C57BL/6NTac
|
|
Mutant Allele(s):
|
Irx1tm1(KOMP)Vlcg/Irx1+
|
|
Age:
|
embryonic day 10.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
Other - See Notes
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS17: embryo |
Strong |
Regionally restricted |
2A
|
Highly expressed in brain, somites, lung, kidney, reproductive organs, eye, limb buds and digits.
|
Specimen
2B:
(close )
|
Genetic Background:
|
involves: C57BL/6NTac
|
|
Mutant Allele(s):
|
Irx1tm1(KOMP)Vlcg/Irx1+
|
|
Age:
|
embryonic day 11.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
Other - See Notes
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS19: embryo |
Strong |
Regionally restricted |
2B
|
Highly expressed in brain, somites, lung, kidney, reproductive organs, eye, limb buds and digits.
|
Specimen
2C:
(close )
|
Genetic Background:
|
involves: C57BL/6NTac
|
|
Mutant Allele(s):
|
Irx1tm1(KOMP)Vlcg/Irx1+
|
|
Age:
|
embryonic day 12.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
Other - See Notes
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS20: embryo |
Strong |
Regionally restricted |
2C
|
Highly expressed in brain, somites, lung, kidney, reproductive organs, eye, limb buds and digits.
|
Specimen
2D:
(close )
|
Genetic Background:
|
involves: C57BL/6NTac
|
|
Mutant Allele(s):
|
Irx1tm1(KOMP)Vlcg/Irx1+
|
|
Age:
|
embryonic day 13.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
Other - See Notes
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS21: embryo |
Strong |
Regionally restricted |
2D
|
Highly expressed in brain, somites, lung, kidney, reproductive organs, eye, limb buds and digits.
|
Specimen
2E:
(close )
|
Genetic Background:
|
involves: C57BL/6NTac
|
|
Mutant Allele(s):
|
Irx1tm1(KOMP)Vlcg/Irx1+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
Other - See Notes
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: brain |
Present |
Regionally restricted |
2E
|
Expression in mid-brain.
|
Specimen
2F:
(close )
|
Genetic Background:
|
involves: C57BL/6NTac
|
|
Mutant Allele(s):
|
Irx1tm1(KOMP)Vlcg/Irx1+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
Other - See Notes
|
Specimen
2G:
(close )
|
Genetic Background:
|
involves: C57BL/6NTac
|
|
Mutant Allele(s):
|
Irx1tm1(KOMP)Vlcg/Irx1+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
Other - See Notes
|
Specimen
2H:
(close )
|
Genetic Background:
|
involves: C57BL/6NTac
|
|
Mutant Allele(s):
|
Irx1tm1(KOMP)Vlcg/Irx1+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Male
|
|
Type:
|
whole mount
|
|
Fixation:
|
Other - See Notes
|
Specimen
2I:
(close )
|
Genetic Background:
|
involves: C57BL/6NTac
|
|
Mutant Allele(s):
|
Irx1tm1(KOMP)Vlcg/Irx1+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
Other - See Notes
|
|
Embedding:
|
Paraffin
|
Specimen
2J:
(close )
|
Genetic Background:
|
involves: C57BL/6NTac
|
|
Mutant Allele(s):
|
Irx1tm1(KOMP)Vlcg/Irx1+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
Other - See Notes
|
|
Embedding:
|
Paraffin
|
Specimen
2K:
(close )
|
Genetic Background:
|
involves: C57BL/6NTac
|
|
Mutant Allele(s):
|
Irx1tm1(KOMP)Vlcg/Irx1+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
Other - See Notes
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: renal tubule |
Present |
Regionally restricted |
2K
|
Expression in intermediate tubules.
|
Specimen
2L:
(close )
|
Genetic Background:
|
involves: C57BL/6NTac
|
|
Mutant Allele(s):
|
Irx1tm1(KOMP)Vlcg/Irx1+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Male
|
|
Type:
|
section
|
|
Fixation:
|
Other - See Notes
|
|
Embedding:
|
Paraffin
|
Specimen
3A E10.5:
(close )
|
Genetic Background:
|
involves: C57BL/6NTac
|
|
Mutant Allele(s):
|
Irx1tm1(KOMP)Vlcg/Irx1+
|
|
Age:
|
embryonic day 10.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
Other - See Notes
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS17: oral region |
Present |
Regionally restricted |
3A E10.5
|
At early stages, expression in entire dental epithelial cell population, including the vestibular lamina.
|
Specimen
3A E11.5:
(close )
|
Genetic Background:
|
involves: C57BL/6NTac
|
|
Mutant Allele(s):
|
Irx1tm1(KOMP)Vlcg/Irx1+
|
|
Age:
|
embryonic day 11.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
Other - See Notes
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS19: dental placode |
Present |
Regionally restricted |
3A E11.5
|
At early stages, expression in entire dental epithelial cell population, including the vestibular lamina.
|
Specimen
3A E12.5:
(close )
|
Genetic Background:
|
involves: C57BL/6NTac
|
|
Mutant Allele(s):
|
Irx1tm1(KOMP)Vlcg/Irx1+
|
|
Age:
|
embryonic day 12.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
Other - See Notes
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS20: tooth bud |
Present |
|
3A E12.5
|
At early stages, expression in entire dental epithelial cell population, including the vestibular lamina.
|
Specimen
3A E13.5:
(close )
|
Genetic Background:
|
involves: C57BL/6NTac
|
|
Mutant Allele(s):
|
Irx1tm1(KOMP)Vlcg/Irx1+
|
|
Age:
|
embryonic day 13.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
Other - See Notes
|
|
Embedding:
|
Paraffin
|
Specimen
3A E15:
(close )
|
Genetic Background:
|
involves: C57BL/6NTac
|
|
Mutant Allele(s):
|
Irx1tm1(KOMP)Vlcg/Irx1+
|
|
Age:
|
embryonic day 15.0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
Other - See Notes
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS23: cap stage tooth |
Present |
Regionally restricted |
3A E15
|
At cap stage, expression limited to area adjacent to oral cavity.
|
Specimen
3C lower incisor:
(close )
|
Genetic Background:
|
involves: C57BL/6NTac
|
|
Mutant Allele(s):
|
Irx1tm1(KOMP)Vlcg/Irx1+
|
|
Age:
|
postnatal day 0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
Other - See Notes
|
|
Embedding:
|
Paraffin
|
Specimen
3C lower incisor (inset left):
postnatal day 0; Irx1tm1(KOMP)Vlcg/Irx1 +
(more  )
Specimen
3C lower incisor (inset left):
(close )
|
Genetic Background:
|
involves: C57BL/6NTac
|
|
Mutant Allele(s):
|
Irx1tm1(KOMP)Vlcg/Irx1+
|
|
Age:
|
postnatal day 0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
Other - See Notes
|
|
Embedding:
|
Paraffin
|
Specimen
3C lower incisor (inset right):
postnatal day 0; Irx1tm1(KOMP)Vlcg/Irx1 +
(more )
Specimen
3C lower incisor (inset right):
(close )
|
Genetic Background:
|
involves: C57BL/6NTac
|
|
Mutant Allele(s):
|
Irx1tm1(KOMP)Vlcg/Irx1+
|
|
Age:
|
postnatal day 0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
Other - See Notes
|
|
Embedding:
|
Paraffin
|
Specimen
3C Molar:
(close )
|
Genetic Background:
|
involves: C57BL/6NTac
|
|
Mutant Allele(s):
|
Irx1tm1(KOMP)Vlcg/Irx1+
|
|
Age:
|
postnatal day 0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
Other - See Notes
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS27: lower jaw molar enamel organ |
Present |
Regionally restricted |
3C Molar
|
In late bell stage teeth, expression limited to outer enamel epithelium, stratum intermedium and stellate reticulum
|
Specimen
3C Molar (inset):
(close )
|
Genetic Background:
|
involves: C57BL/6NTac
|
|
Mutant Allele(s):
|
Irx1tm1(KOMP)Vlcg/Irx1+
|
|
Age:
|
postnatal day 0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
Other - See Notes
|
|
Embedding:
|
Paraffin
|
Specimen
3E (left):
(close )
|
Genetic Background:
|
involves: C57BL/6NTac
|
|
Mutant Allele(s):
|
Irx1tm1(KOMP)Vlcg/Irx1+
|
|
Age:
|
postnatal day 30
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
Other - See Notes
|
Specimen
3E (right):
(close )
|
Genetic Background:
|
involves: C57BL/6NTac
|
|
Mutant Allele(s):
|
Irx1tm1(KOMP)Vlcg/Irx1+
|
|
Age:
|
postnatal day 30
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
Other - See Notes
|
Specimen
8C Irx1+/-:
(close )
|
Genetic Background:
|
involves: C57BL/6NTac
|
|
Mutant Allele(s):
|
Irx1tm1(KOMP)Vlcg/Irx1+
|
|
Age:
|
postnatal day 0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
Other - See Notes
|
|
Embedding:
|
Paraffin
|
Specimen
8C Irx1-/-:
(close )
|
Genetic Background:
|
involves: C57BL/6NTac
|
|
Mutant Allele(s):
|
Irx1tm1(KOMP)Vlcg/Irx1tm1(KOMP)Vlcg
|
|
Age:
|
postnatal day 0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
Other - See Notes
|
|
Embedding:
|
Paraffin
|
|
Analysis Tools