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Gene Expression Data
Assay Details
Assay
Reference: J:248919 Yu W, et al., Irx1 regulates dental outer enamel epithelial and lung alveolar type II epithelial differentiation. Dev Biol. 2017 Sep 1;429(1):44-55
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7258178
Gene symbol: Lef1
Gene name: lymphoid enhancer binding factor 1
Results
Specimen 8A Irx1+/+: embryonic day 18.5 (more )
Note: Triple labeled: green - Lef1; red - Sox2 (assay MGI:7258179); blue - DAPI.
Structure Level Pattern Image Note
TS26: lower jaw incisor mesenchyme Present 8A Irx1+/+ (merge) , 8A Irx1+/+ Lef-1
Specimen 8A Irx1-/-: embryonic day 18.5; Irx1tm1(KOMP)Vlcg/Irx1tm1(KOMP)Vlcg (more )
Note: Triple labeled: green - Lef1; red - Sox2 (assay MGI:7258179); blue - DAPI.
Structure Level Pattern Image Note
TS26: lower jaw incisor mesenchyme Weak Regionally restricted 8A Irx1-/- (merge) , 8A Irx1-/- Lef-1 Expression reduced in surrounding lingual dental mesenchyme, adjacent to region of increased Sox2-expressing epithelial cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
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