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Gene Expression Data
Assay Details
Assay
Reference: J:110714 Barrionuevo F, et al., Sox9 is required for notochord maintenance in mice. Dev Biol. 2006 Jul 1;295(1):128-40
Assay type: RNA in situ
MGI Accession ID: MGI:7258379
Gene symbol: T
Gene name: brachyury, T-box transcription factor T
Probe: brachyury probe2
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 4F: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: notochord Present 4F Expression clearly visible as a continuous stripe along midline.
Specimen 4G: embryonic day 8.5; Sox9tm1Gsr/Sox9tm1Gsr, Krt19tm1(cre)Mmt/Krt19+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS13: notochord Present 4G Expression unchanged in mutant compared with wild type.
Specimen 4H: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: notochord Present 4H Expression clearly visible as a continuous stripe along midline.
Specimen 4I: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: notochord Present Regionally restricted 4I Expression becomes dicontinuous in cervical and thoracic regions in mutant starting from E9.5.
Specimen 4J: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: notochord Present 4J Expression clearly visible as a continuous stripe along midline.
Specimen 4K: embryonic day 10.5; Sox9tm1Gsr/Sox9tm1Gsr, Krt19tm1(cre)Mmt/Krt19+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: notochord Present Regionally restricted 4K Loss of continuous expression in mutant progressively expanded posterioly with islands of expressing notochord tissue remaining along midline.
Specimen 4L: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: notochord Present 4L
Specimen 4M: embryonic day 10.5; Sox9tm1Gsr/Sox9tm1Gsr, Krt19tm1(cre)Mmt/Krt19+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: notochord Present Regionally restricted 4M Loss of continuous expression in mutant progressively expanded posterioly with islands of expressing notochord tissue remaining along midline.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory