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Gene Expression Data
Assay Details
Assay
Reference: J:110714 Barrionuevo F, et al., Sox9 is required for notochord maintenance in mice. Dev Biol. 2006 Jul 1;295(1):128-40
Assay type: RNA in situ
MGI Accession ID: MGI:7258386
Gene symbol: Nkx3-2
Gene name: NK3 homeobox 2
Probe: Bapx1 probe3
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen E10.5 wt not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: sclerotome Present Regionally restricted Expression in ventro-medial sclerotome.
Specimen E10.5 mut not shown: embryonic day 10.5; Sox9tm1Gsr/Sox9tm1Gsr, Krt19tm1(cre)Mmt/Krt19+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: sclerotome Present Regionally restricted Expression unchanged in mutant compared with wild type.
Specimen 5O: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: sclerotome Strong Regionally restricted 5O Highly expressed in presumptive intervertebral region.
Specimen 5P: embryonic day 11.5; Sox9tm1Gsr/Sox9tm1Gsr, Krt19tm1(cre)Mmt/Krt19+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: sclerotome Present Regionally restricted 5P Expression maintained in sclerotome, but in an unsegmental manner.
Specimen 6I: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: sclerotome Present Regionally restricted 6I Expression in narrow zones of intervertebral regions.
Specimen 6M: embryonic day 13.5; Sox9tm1Gsr/Sox9tm1Gsr, Krt19tm1(cre)Mmt/Krt19+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: sclerotome Present Regionally restricted 6M Expression in mesenchyme surrounding cartilage cores.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory