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Gene Expression Data
Assay Details
Assay
Reference: J:110714 Barrionuevo F, et al., Sox9 is required for notochord maintenance in mice. Dev Biol. 2006 Jul 1;295(1):128-40
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7258387
Gene symbol: Sox9
Gene name: SRY (sex determining region Y)-box 9
Antibody: anti-Sox9
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 1C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: notochord Present 1C
TS17: sclerotome Present Regionally restricted 1C Expression in ventral sclerotome cells of peri-notochordal region.
Specimen 4D: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: notochord Present 4D
Specimen 4E: embryonic day 9.5; Sox9tm1Gsr/Sox9tm1Gsr, Krt19tm1(cre)Mmt/Krt19+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: notochord Present Scattered 4E Expression largely absent except for some expressing notochord cells scattered along its anterior-posterior extenstion.
Specimen 4T: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: notochord Present Regionally restricted 4T Expression in migrating notochord cells.
TS17: sclerotome Present 4T
Specimen 4U: embryonic day 10.5; Sox9tm1Gsr/Sox9tm1Gsr, Krt19tm1(cre)Mmt/Krt19+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: notochord Present 4U Expression in notochord remnants.
TS17: sclerotome Present 4U Number of expressing cells in sclerotome is reduced compared to wildtype.
Specimen 6A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: notochord Present 6A
TS20: vertebral cartilage condensation Present Regionally restricted 6A Expression in chondrifying areas of vertebral bodies.
Specimen 6B: embryonic day 12.5; Sox9tm1Gsr/Sox9tm1Gsr, Krt19tm1(cre)Mmt/Krt19+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: notochord Present 6B
TS20: vertebral cartilage condensation Present Regionally restricted 6B In areas with functional notochordal tissue, expression in condensed sclerotomal cells starting to initiate chondrogenesis.
Specimen 6C: embryonic day 12.5; Sox9tm1Gsr/Sox9tm1Gsr, Krt19tm1(cre)Mmt/Krt19+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: sclerotome Present Regionally restricted 6C In regions devoid of notochord cells, such as the entire lumbar region. no expression in ventral medial sclerotome.
Specimen 6D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: notochord Present 6D
TS21: vertebral cartilage condensation Present Regionally restricted 6D Expression in chondrifying areas of vertebral bodies.
Specimen 6E: embryonic day 13.5; Sox9tm1Gsr/Sox9tm1Gsr, Krt19tm1(cre)Mmt/Krt19+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: notochord Present 6E Aggregates of expressing cells deposited a cartilage matrix.
TS21: vertebral cartilage condensation Present Regionally restricted 6E In areas with functional notochordal tissue, expression in condensed sclerotomal cells starting to initiate chondrogenesis.
Specimen 6F: embryonic day 13.5; Sox9tm1Gsr/Sox9tm1Gsr, Krt19tm1(cre)Mmt/Krt19+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: sclerotome Present Regionally restricted 6F In regions devoid of notochord cells, such as the entire lumbar region. no expression in ventral medial sclerotome.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory