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Gene Expression Data
Assay Details
Assay
Reference: J:308975 Takenoshita M, et al., Cell lineage- and expression-based inference of the roles of forkhead box transcription factor Foxc2 in craniofacial development. Dev Dyn. 2021 Aug;250(8):1125-1139
Assay type: RNA in situ
MGI Accession ID: MGI:7261297
Gene symbol: Foxc1
Gene name: forkhead box C1
Probe: Foxc1 probe4
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4F: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: head mesenchyme Present 4F
TS13: somite Present 4F
Specimen 4G: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: head mesenchyme Present 4G
TS15: somite Present 4G
TS15: forelimb bud mesenchyme Present 4G
Specimen 4H: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: head mesenchyme Present 4H
TS17: somite Present 4H
TS17: forelimb bud mesenchyme Present 4H
Specimen 4I: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: head mesenchyme Present 4I
Specimen 4J: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: head Present 4J Authors report expression in a similar manner to that of Foxc2.
Specimen 5D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cranium Present Regionally restricted 5D Expression in cranial base.
TS20: nose Present Regionally restricted 5D Expression in nasal capsule.
TS20: otic capsule Present 5D
Specimen 5E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cranium Present Regionally restricted 5E Expression in cranial base.
TS20: tongue Absent 5E
Specimen 5F: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: nose Present Regionally restricted 5F nasal capsule.
TS20: otic capsule Present 5F
TS20: middle ear mesenchyme Present Regionally restricted 5F Expression in auditory ossicles.
Specimen 5J: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: chondrocranium Present Regionally restricted 5J Similar pattern of expression in cartilage of chondrocranium as seen at E12.5.
TS22: perichondrium Strong 5J Vigorous expression in perichondrium.
Specimen 5K: embryonic day 14.5 (more )
Structure Cell Type Level Pattern Image Note
TS22: chondrocranium chondrocyte Trace 5K Faint or no expression in chondrocytes.
TS22: tongue Absent 5K
Specimen 5L: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: chondrocranium Present Regionally restricted 5L Similar pattern of expression in cartilage of chondrocranium as seen at E12.5.
Specimen 7B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: palatal shelf Trace 7B
TS20: tongue Absent 7B
TS20: Meckel's cartilage Present Regionally restricted 7B Expression in perichondrium of Meckel's cartilage.
TS20: head mesenchyme Present Regionally restricted 7B No expression in mesenchyme between genioglossus and Meckel's cartilage.
Specimen 8C: embryonic day 12.5; Foxc2tm1.1Miu/Foxc2tm1.1Miu (more )
Structure Level Pattern Image Note
TS20: head Present 8C
Specimen 8D: embryonic day 12.5; Foxc2tm1.1Miu/Foxc2tm1.1Miu, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: head Present 8D Expression not affected compared to control.
Specimen 10B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS20: tongue Absent 10B
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/09/2024
MGI 6.24 		The Jackson Laboratory