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Gene Expression Data
Assay Details
Assay
Reference: J:318768 Carpentieri JA, et al., Endosomal trafficking defects alter neural progenitor proliferation and cause microcephaly. Nat Commun. 2022 Jan 10;13(1):16
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7264458
Gene symbol: Rbfox3
Gene name: RNA binding protein, fox-1 homolog (C. elegans) 3
Antibody: Anti-NeuN (EPR12763; ab177487)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 1g WT: postnatal day 0 (more )
Structure Cell Type Level Pattern Image Note
TS27: cortical plate neuron Present 1g WT

Specimen 1g WDR81-/-: postnatal day 0; Wdr81em1Curie/Wdr81em1Curie (more )
Structure Cell Type Level Pattern Image Note
TS27: cortical plate neuron Present 1g WDR81-/- Reduced numbers of expressing neurons at P0.

Specimen E12.5 WT not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: brain Present

Specimen E12.5 WDR81-/- not shown: embryonic day 12.5; Wdr81em1Curie/Wdr81em1Curie (more )
Structure Level Pattern Image Note
TS20: brain Present

Specimen 2g NEUN WT: embryonic day 14.5 (more )
Structure Cell Type Level Pattern Image Note
TS22: brain neuron Present 2g NEUN WT

Specimen 2g NEUN WDR81-/-: embryonic day 14.5; Wdr81em1Curie/Wdr81em1Curie (more )
Structure Cell Type Level Pattern Image Note
TS22: brain neuron Present 2g NEUN WDR81-/- Authors report reduction of proportion of neurons at mid and late neurogenesis.

Specimen E16.5 WT not shown: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: brain Present

Specimen E16.5 WDR81-/- not shown: embryonic day 16.5; Wdr81em1Curie/Wdr81em1Curie (more )
Structure Level Pattern Image Note
TS24: brain Present Authors report reduction of proportion of neurons at mid and late neurogenesis.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory