About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:318768 Carpentieri JA, et al., Endosomal trafficking defects alter neural progenitor proliferation and cause microcephaly. Nat Commun. 2022 Jan 10;13(1):16
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7264463
Gene symbol: Eomes
Gene name: eomesodermin
Antibody: anti-TBR2/EOMES (AF6166)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen E12.5 WT not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: brain Present
Specimen E12.5 WDR81-/- not shown: embryonic day 12.5; Wdr81em1Curie/Wdr81em1Curie (more )
Structure Level Pattern Image Note
TS20: brain Present
Specimen 2b WT: embryonic day 14.5 (more )
Note: Double labeled: yellow - Tbr2 (Eomes); red - phospho-Histone H3.
Structure Level Pattern Image Note
TS22: brain Present 2b WT Expression in intermediate progenitors.
Specimen 2b WDR81-/-: embryonic day 14.5; Wdr81em1Curie/Wdr81em1Curie (more )
Note: Double labeled: yellow - Tbr2 (Eomes); red - phospho-Histone H3.
Structure Level Pattern Image Note
TS22: brain Present 2b WDR81-/- Expression in intermediate progenitors.
Specimen E16.5 WT not shown: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: brain Present
Specimen E16.5 WDR81-/- not shown: embryonic day 16.5; Wdr81em1Curie/Wdr81em1Curie (more )
Structure Level Pattern Image Note
TS24: brain Present
Specimen 2g TBR2 WT: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: brain Present 2g TBR2 WT
Specimen 2g TBR2 WDR81-/-: embryonic day 14.5; Wdr81em1Curie/Wdr81em1Curie (more )
Structure Level Pattern Image Note
TS22: brain Present 2g TBR2 WDR81-/- No decrease in proportion of progenitors.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory