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Gene Expression Data
Assay Details
Assay
Reference: J:318768 Carpentieri JA, et al., Endosomal trafficking defects alter neural progenitor proliferation and cause microcephaly. Nat Commun. 2022 Jan 10;13(1):16
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7264464
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-cleaved Caspase-3 (Asp175; #9661)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 2h WT: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: brain Ambiguous 2h CC3 WT Expression almost undetectable.
Specimen 2h WDR81-/-: embryonic day 14.5; Wdr81em1Curie/Wdr81em1Curie (more )
Structure Level Pattern Image Note
TS22: brain Absent 2h CC3 WDR81-/- Authors report absence of apoptosis induction.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory