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Gene Expression Data
Assay Details
Assay
Reference: J:318768 Carpentieri JA, et al., Endosomal trafficking defects alter neural progenitor proliferation and cause microcephaly. Nat Commun. 2022 Jan 10;13(1):16
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7264465
Gene symbol: Eea1
Gene name: early endosome antigen 1
Antibody: anti-EEA1 (610457)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 4c CONTROL: embryonic day 14.5 (more )
Note: Double labeled: white - Eea1; red - actin.
Structure Level Pattern Image Note
TS22: cerebral cortex ventricular layer Present 4c CONTROL
Specimen 4c WDR81-/-: embryonic day 14.5; Wdr81em1Curie/Wdr81em1Curie (more )
Note: Double labeled: white - Eea1; red - actin.
Structure Level Pattern Image Note
TS22: cerebral cortex ventricular layer Present 4c WDR81-/- Authors report specific alteration in early endosomes, which appear strongly enlarged.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory