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Gene Expression Data
Assay Details
Assay
Reference: J:310902 Hayashi S, et al., The nephric mesenchyme lineage of intermediate mesoderm is derived from Tbx6-expressing derivatives of neuro-mesodermal progenitors via BMP-dependent Osr1 function. Dev Biol. 2021 Oct;478:155-162
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7286069
Gene symbol: Pax2
Gene name: paired box 2
Antibody: anti-Pax2 (#901001, #PRB-276P)
Detection system: Secondary antibody
Results
Specimen 2O: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: nephric duct Present 2O
TS17: nephrogenic cord Present 2O
Specimen 2P: embryonic day 10.5; Tbx6tm1Pa/Tbx6tm1Pa (more )
Structure Level Pattern Image Note
TS17: nephric duct Absent 2P
TS17: nephrogenic cord Absent 2P
TS17: neural tube Present 2P Ectopic neural tubes developed from paraxial mesoderm.
Specimen 3C: embryonic day 9.5 (more )
Note: Forelimb level. Triple labeled: red - Pax2; white - Cdh1 (assay MGI:7286081); green - Sox2 (assay MGI:7286068).
Structure Level Pattern Image Note
TS15: nephric duct Present 3C
Specimen 3D: embryonic day 9.5; Tbx6tm1Pa/Tbx6tm1Pa (more )
Note: Forelimb level. Triple labeled: red - Pax2; white - Cdh1 (assay MGI:7286081); green - Sox2 (assay MGI:7286068).
Structure Level Pattern Image Note
TS15: nephric duct Present 3D Expression was reduced with a smaller size at the forelimb level.
Specimen 3G: embryonic day 9.5 (more )
Note: Hindlimb level. Triple labeled: red - Pax2; white - Cdh1 (assay MGI:7286081); green - Sox2 (assay MGI:7286068).
Structure Level Pattern Image Note
TS15: nephric duct Present 3G
Specimen 3H: embryonic day 9.5; Tbx6tm1Pa/Tbx6tm1Pa (more )
Note: Hindlimb level. Triple labeled: red - Pax2; white - Cdh1 (assay MGI:7286081); green - Sox2 (assay MGI:7286068).
Structure Level Pattern Image Note
TS15: nephric duct Present Regionally restricted 3H Expression was completely lost at the hindlimb level, suggesting a defect in the posterior extension.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
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