Col1a1 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:171508 Ikegami D, et al., Sox9 sustains chondrocyte survival and hypertrophy in part through Pik3ca-Akt pathways. Development. 2011 Apr;138(8):1507-19
Assay type:	RNA in situ
MGI Accession ID:	MGI:7286486
Gene symbol:	Col1a1
Gene name:	collagen, type I, alpha 1

Probe:	Col1a1 probe20
Probe preparation:	Antisense labelled with digoxigenin RNA

Results

Specimen 3D Sox9^flox/+: embryonic day 14.5; Sox9^tm2Crm/Sox9⁺ (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS22: humerus cartilage condensation	chondrocyte	Absent		3D Col1a1 Sox9^flox/+

Specimen 3D 11Prom-Cre; Sox9^flox/flox: embryonic day 14.5; Sox9^tm2Crm/Sox9^tm2Crm, Tg(Col11a2-cre)2Ntsu/0 (more

)
Note: Conditional mutant.

Structure	Cell Type	Level	Pattern	Image	Note
TS22: humerus cartilage condensation	chondrocyte	Present	Regionally restricted	3D Col1a1 11Prom-Cre; Sox9^flox/flox	Ectopic expression was detected in the chondrocytes in the central region of conditional mutant humeral cartilage.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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