Gene Expression Data
Assay Details
Assay
|
Reference:
|
J:326256
Lee JM, et al., MSX1 Drives Tooth Morphogenesis Through Controlling Wnt Signaling Activity. J Dent Res. 2022 Jul;101(7):832-839
|
Assay type:
|
RNA in situ
|
MGI Accession ID:
|
MGI:7311643
|
Gene symbol:
|
Sostdc1
|
Gene name:
|
sclerostin domain containing 1
|
Probe:
|
Sostdc1 probe2
|
Probe preparation:
|
labelled with digoxigenin
|
Visualized with:
|
Alkaline phosphatase
|
|
Results
|
Specimen
1D Mx:
embryonic day 12.5
(more )
Specimen
1D Mx:
(close )
Genetic Background:
|
involves: 129
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: dental placode |
Present |
Regionally restricted |
1D Mx
|
Expression in distal tip of tooth germ weaker than for Lef1.
|
Specimen
1D' Mx:
(close )
Genetic Background:
|
involves: 129S4/SvJae
|
Mutant Allele(s):
|
Msx1tm1Rilm/Msx1tm1Rilm
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: dental placode |
Weak |
|
1D' Mx
|
Author report a moderate and gradual decrease in expression.
|
Specimen
1D Mn:
embryonic day 12.5
(more )
Specimen
1D Mn:
(close )
Genetic Background:
|
involves: 129
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: dental placode |
Present |
Regionally restricted |
1D Mn
|
Expression in distal tip of tooth germ weaker than for Lef1.
|
Specimen
1D' Mn:
(close )
Genetic Background:
|
involves: 129S4/SvJae
|
Mutant Allele(s):
|
Msx1tm1Rilm/Msx1tm1Rilm
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: dental placode |
Weak |
|
1D' Mn
|
Author report a moderate and gradual decrease in expression, expecially in the mandible.
|
Specimen
1E Mx:
embryonic day 13.5
(more )
Specimen
1E Mx:
(close )
Genetic Background:
|
involves: 129
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS21: tooth bud |
Present |
Regionally restricted |
1E Mx
|
Expression in distal tip of tooth germ weaker than for Lef1.
|
Specimen
1E' Mx:
(close )
Genetic Background:
|
involves: 129S4/SvJae
|
Mutant Allele(s):
|
Msx1tm1Rilm/Msx1tm1Rilm
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS21: tooth bud |
Weak |
|
1E' Mx
|
Author report a moderate and gradual decrease in expression.
|
Specimen
1E Mn:
embryonic day 13.5
(more )
Specimen
1E Mn:
(close )
Genetic Background:
|
involves: 129
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS21: tooth bud |
Present |
Regionally restricted |
1E Mn
|
Expression in distal tip of tooth germ weaker than for Lef1.
|
Specimen
1E' Mn:
(close )
Genetic Background:
|
involves: 129S4/SvJae
|
Mutant Allele(s):
|
Msx1tm1Rilm/Msx1tm1Rilm
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS21: tooth bud |
Weak |
|
1E' Mn
|
Author report a moderate and gradual decrease in expression, expecially in the mandible.
|
Specimen
1F Mx:
embryonic day 14.5
(more )
Specimen
1F Mx:
(close )
Genetic Background:
|
involves: 129
|
Age:
|
embryonic day 14.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: cap stage tooth |
Present |
Regionally restricted |
1F Mx
|
Expression in distal tip of tooth germ weaker than for Lef1.
|
Specimen
1F' Mx:
(close )
Genetic Background:
|
involves: 129S4/SvJae
|
Mutant Allele(s):
|
Msx1tm1Rilm/Msx1tm1Rilm
|
Age:
|
embryonic day 14.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: cap stage tooth |
Weak |
|
1F' Mx
|
Author report a moderate and gradual decrease in expression.
|
Specimen
1F Mn:
embryonic day 14.5
(more )
Specimen
1F Mn:
(close )
Genetic Background:
|
involves: 129
|
Age:
|
embryonic day 14.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: cap stage tooth |
Present |
Regionally restricted |
1F Mn
|
Expression in distal tip of tooth germ weaker than for Lef1.
|
Specimen
1F' Mn:
(close )
Genetic Background:
|
involves: 129S4/SvJae
|
Mutant Allele(s):
|
Msx1tm1Rilm/Msx1tm1Rilm
|
Age:
|
embryonic day 14.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: cap stage tooth |
Weak |
|
1F' Mn
|
Author report a moderate and gradual decrease in expression, expecially in the mandible.
|
|