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Gene Expression Data
Assay Details
Assay
Reference: J:248783 Xie WR, et al., An Atoh1-S193A Phospho-Mutant Allele Causes Hearing Deficits and Motor Impairment. J Neurosci. 2017 Sep 6;37(36):8583-8594
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7328545
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-activated Caspase 3 (AF835)
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 5A lacZ/+ Base: embryonic day 16.5; Atoh1tm2Hzo/Atoh1+ (more )
Note: Double labeled: red - Casp3; green - p27Kip1 (Cdkn1b assay MGI:7328544).
Structure Level Pattern Image Note
TS24: cochlea epithelium Absent 5A lacZ/+ Base
Specimen 5A lacZ/+ Mid: embryonic day 16.5; Atoh1tm2Hzo/Atoh1+ (more )
Note: Double labeled: red - Casp3; green - p27Kip1 (Cdkn1b assay MGI:7328544).
Structure Level Pattern Image Note
TS24: cochlea epithelium Absent 5A lacZ/+ Mid
Specimen 5A lacZ/+ Apex: embryonic day 16.5; Atoh1tm2Hzo/Atoh1+ (more )
Note: Double labeled: red - Casp3; green - p27Kip1 (Cdkn1b assay MGI:7328544).
Structure Level Pattern Image Note
TS24: cochlea epithelium Absent 5A lacZ/+ Apex
Specimen 5A null Base: embryonic day 16.5; Atoh1tm4.1Hzo/Atoh1tm4.1Hzo (more )
Note: Double labeled: red - Casp3; green - p27Kip1 (Cdkn1b assay MGI:7328544).
Structure Level Pattern Image Note
TS24: cochlea epithelium Present Single cells 5A null Base
Specimen 5A null Mid: embryonic day 16.5; Atoh1tm4.1Hzo/Atoh1tm4.1Hzo (more )
Note: Double labeled: red - Casp3; green - p27Kip1 (Cdkn1b assay MGI:7328544).
Structure Level Pattern Image Note
TS24: cochlea epithelium Present Single cells 5A null Mid
Specimen 5A null Apex: embryonic day 16.5; Atoh1tm4.1Hzo/Atoh1tm4.1Hzo (more )
Note: Double labeled: red - Casp3; green - p27Kip1 (Cdkn1b assay MGI:7328544).
Structure Level Pattern Image Note
TS24: cochlea epithelium Present Single cells 5A null Apex
Specimen 5A 193A/lacZ Base: embryonic day 16.5; Atoh1tm2Hzo/Atoh1tm7.1Hzo (more )
Note: Double labeled: red - Casp3; green - p27Kip1 (Cdkn1b assay MGI:7328544).
Structure Level Pattern Image Note
TS24: cochlea epithelium Present Single cells 5A S193A/lacZ Base
Specimen 5A 193A/lacZ Mid: embryonic day 16.5; Atoh1tm2Hzo/Atoh1tm7.1Hzo (more )
Note: Double labeled: red - Casp3; green - p27Kip1 (Cdkn1b assay MGI:7328544).
Structure Level Pattern Image Note
TS24: cochlea epithelium Present Single cells 5A S193A/lacZ Mid
Specimen 5A 193A/lacZ Apex: embryonic day 16.5; Atoh1tm2Hzo/Atoh1tm7.1Hzo (more )
Note: Double labeled: red - Casp3; green - p27Kip1 (Cdkn1b assay MGI:7328544).
Structure Level Pattern Image Note
TS24: cochlea epithelium Present Single cells 5A S193A/lacZ Apex
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory