Gene Expression Data
Assay Details
Assay
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Reference:
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J:149884
Kim T, et al., NRH2 is a trafficking switch to regulate sortilin localization and permit proneurotrophin-induced cell death. EMBO J. 2009 Jun 3;28(11):1612-23
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7331571
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Gene symbol:
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Nradd
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Gene name:
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neurotrophin receptor associated death domain
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Results
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Specimen
1Aa:
postnatal day 1
(more )
Note: Double labeled: green - Nradd; red - Sort1 (assay MGI:7331653).
Specimen
1Aa:
(close )
Genetic Background:
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C57BL/6
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Age:
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postnatal day 1
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Note:
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Double labeled: green - Nradd; red - Sort1 (assay MGI:7331653).
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS27: dorsal root ganglion |
sensory neuron of dorsal root ganglion |
Present |
Regionally restricted |
1Aa Merged
,
1Aa Nrh2
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Co-immunolabeling was detected with Sortilin in most dorsal root ganglion neurons.
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Specimen
1Ab:
postnatal day 1
(more )
Note: Double labeled: green - Nradd; red - Ngfr (assay MGI:7331654).
Specimen
1Ab:
(close )
Genetic Background:
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C57BL/6
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Age:
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postnatal day 1
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
|
Note:
|
Double labeled: green - Nradd; red - Ngfr (assay MGI:7331654).
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS27: dorsal root ganglion |
sensory neuron of dorsal root ganglion |
Present |
Regionally restricted |
1Ab Merged
,
1Ab Nrh2
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Expression was detected in most dorsal root ganglion neurons. A subpopulation of neurons was co-immunolabeled with Ngfr.
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Specimen
S1a:
postnatal day 1
(more )
Note: Double labeled: red - Nradd; green - Sort1 (assay MGI:7331653).
Specimen
S1a:
(close )
Genetic Background:
|
C57BL/6
|
Age:
|
postnatal day 1
|
Sex:
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Not Specified
|
Type:
|
section
|
Embedding:
|
Paraffin
|
Note:
|
Double labeled: red - Nradd; green - Sort1 (assay MGI:7331653).
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS27: spinal cord |
spinal cord motor neuron |
Present |
Regionally restricted |
S1a merged
,
S1a Nrh2
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Co-expression with Sortilin was observed in a subset of spinal motor neurons.
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Specimen
S1b:
postnatal day 1
(more )
Note: Double labeled: red - Nradd; green - Ngfr (assay MGI:7331654).
Specimen
S1b:
(close )
Genetic Background:
|
C57BL/6
|
Age:
|
postnatal day 1
|
Sex:
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Not Specified
|
Type:
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section
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Embedding:
|
Paraffin
|
Note:
|
Double labeled: red - Nradd; green - Ngfr (assay MGI:7331654).
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS27: spinal cord |
spinal cord motor neuron |
Present |
Regionally restricted |
S1b merged
,
S1b Nrh2
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Co-expression with Ngfr was observed in a subset of spinal motor neurons.
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Specimen
S2B:
embryonic day 15.5
(more )
Note: Double labeled: red - Nradd; green - Sort1 (assay MGI:7331653).
Specimen
S2B:
(close )
Genetic Background:
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C57BL/6
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Note:
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Double labeled: red - Nradd; green - Sort1 (assay MGI:7331653).
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS23: retina layer |
retinal ganglion cell |
Strong |
Regionally restricted |
S2B Merged
,
S2B Nrh2
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Expression was high in the ganglion cell layer. A subset of cells in the ganglion cell layer were co-labeled with Sortilin.
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Specimen
S2C:
postnatal day 1
(more )
Note: Double labeled: red - Nradd; green - Sort1 (assay MGI:7331653).
Specimen
S2C:
(close )
Genetic Background:
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C57BL/6
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Age:
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postnatal day 1
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
|
Note:
|
Double labeled: red - Nradd; green - Sort1 (assay MGI:7331653).
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: retina ganglion cell layer |
Weak |
Regionally restricted |
S2C Nrh2
,
S2C Merged
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Expression was markedly reduced in the ganglion cell layer.
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