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Gene Expression Data
Assay Details
Assay
Reference: J:327232 Wu JPH, et al., The Transcription Factor Pou3f1 Sheds Light on the Development and Molecular Diversity of Glutamatergic Cerebellar Nuclear Neurons in the Mouse. Front Mol Neurosci. 2022;15:921901
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7336070
Gene symbol: Irx3
Gene name: Iroquois related homeobox 3
Antibody: anti-Irx3
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 9A: postnatal day 6 (more )
Note: Double labeled: red - Irx3; green - Atoh1 reporter (assay MGI:7336071).
Structure Cell Type Level Pattern Image Note
TS28: cerebellum cerebellar neuron Present Regionally restricted 9A Co-expression with Pou3f1 in ~55% of Pou3f1-expressing cerebellar nucleus (CN) neurons.
TS28: fastigial nucleus Present Clusters 9A Expression in small cluster of cells not expressing Pou3f1.
Specimen 9B,B': postnatal day 6 (more )
Note: Double labeled: red - Irx3; green - Atoh1 reporter (assay MGI:7336071).
Structure Level Pattern Image Note
TS28: cerebellum interpositus nucleus Present 9B' , 9B Co-expression with Pou3f1 predominantly in interposed nucleus.
Specimen 9C,C': postnatal day 6 (more )
Note: Double labeled: red - Irx3; green - Atoh1 reporter (assay MGI:7336071).
Structure Level Pattern Image Note
TS28: dentate nucleus Present 9C , 9C' Minor co-expression with Pou3f1 in dentate nucleus.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/22/2024
MGI 6.24 		The Jackson Laboratory