About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:306393 Ofek S, et al., Notch signaling is a critical initiator of roof plate formation as revealed by the use of RNA profiling of the dorsal neural tube. BMC Biol. 2021 Apr 23;19(1):84
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7339065
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Antibody: anti-Islet-1 (40-3A4)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 8M: embryonic day 10.5 (more )
Structure Cell Type Level Pattern Image Note
TS17: neural tube lateral wall dorsal horn interneuron Present Regionally restricted 8M Expressed in the dI3 interneuron progenitors.
Specimen 8N: embryonic day 10.5; Mib1tm2Kong/Mib1tm2Kong, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS17: neural tube lateral wall dorsal horn interneuron Present Regionally restricted 8N Expression was also shifted dorsal-ward, but their total amount was unaffected.
Specimen 8O: embryonic day 11.5 (more )
Structure Cell Type Level Pattern Image Note
TS19: neural tube lateral wall dorsal horn interneuron Present Regionally restricted 8O Expressed in the dI3 interneuron progenitors.
Specimen 8P: embryonic day 11.5; Mib1tm2Kong/Mib1tm2Kong, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS19: neural tube lateral wall dorsal horn interneuron Present Regionally restricted 8P Expression was also shifted dorsal-ward, but their total amount was unaffected.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/15/2024
MGI 6.24 		The Jackson Laboratory