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Gene Expression Data
Assay Details
Assay
Reference: J:306393 Ofek S, et al., Notch signaling is a critical initiator of roof plate formation as revealed by the use of RNA profiling of the dorsal neural tube. BMC Biol. 2021 Apr 23;19(1):84
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7339066
Gene symbol: Tfap2a
Gene name: transcription factor AP-2, alpha
Antibody: clone 3B5
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 8Q: embryonic day 10.5 (more )
Structure Cell Type Level Pattern Image Note
TS17: neural tube lateral wall dorsal horn interneuron Present Regionally restricted 8Q Expressed in the dI2-5 interneuron progenitors.
Specimen 8R: embryonic day 10.5; Mib1tm2Kong/Mib1tm2Kong, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS17: neural tube lateral wall dorsal horn interneuron Present Regionally restricted 8R Expression was shifted dorsal-ward, with significantly increased total amount.
Specimen 8S: embryonic day 11.5 (more )
Structure Cell Type Level Pattern Image Note
TS19: neural tube lateral wall dorsal horn interneuron Present Regionally restricted 8S Expressed in the dI2-5 interneuron progenitors.
Specimen 8T: embryonic day 11.5; Mib1tm2Kong/Mib1tm2Kong, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS19: neural tube lateral wall dorsal horn interneuron Present Regionally restricted 8T Expression was shifted dorsal-ward, with significantly increased total amount.
Specimen S10A: embryonic day 9.5 (more )
Note: Double labeled: green - Tfap2a; red - Casp3 (assay MGI:7339068).
Structure Cell Type Level Pattern Image Note
TS15: migrating neural crest migratory trunk neural crest cell Present S10A
Specimen S10B: embryonic day 9.5; Mib1tm2Kong/Mib1tm2Kong, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. Double labeled: green - Tfap2a; red - Casp3 (assay MGI:7339068).
Structure Cell Type Level Pattern Image Note
TS15: migrating neural crest migratory trunk neural crest cell Present S10B Similar as in the wild-type.
Specimen S10C: embryonic day 10.5 (more )
Note: Double labeled: green - Tfap2a; red - Casp3 (assay MGI:7339068).
Structure Cell Type Level Pattern Image Note
TS17: neural tube lateral wall dorsal horn interneuron Present Regionally restricted S10C Expressed in the dI2-5 interneuron progenitors.
TS17: dorsal root ganglion Present S10C
Specimen S10D: embryonic day 10.5; Mib1tm2Kong/Mib1tm2Kong, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. Double labeled: green - Tfap2a; red - Casp3 (assay MGI:7339068).
Structure Cell Type Level Pattern Image Note
TS17: neural tube lateral wall dorsal horn interneuron Present Regionally restricted S10D Expression was shifted dorsal-ward, with significantly increased total amount.
TS17: dorsal root ganglion Present S10D
Specimen S10E: embryonic day 11.5 (more )
Note: Double labeled: green - Tfap2a; red - Casp3 (assay MGI:7339068).
Structure Cell Type Level Pattern Image Note
TS19: neural tube lateral wall dorsal horn interneuron Present Regionally restricted S10E Expressed in the dI2-5 interneuron progenitors.
TS19: dorsal root ganglion Present S10E
Specimen S10F: embryonic day 11.5; Mib1tm2Kong/Mib1tm2Kong, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. Double labeled: green - Tfap2a; red - Casp3 (assay MGI:7339068).
Structure Cell Type Level Pattern Image Note
TS19: neural tube lateral wall dorsal horn interneuron Present Regionally restricted S10F Expression was shifted dorsal-ward, with significantly increased total amount.
TS19: dorsal root ganglion Present S10F
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/15/2024
MGI 6.24 		The Jackson Laboratory