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Gene Expression Data
Assay Details
Assay
Reference: J:306393 Ofek S, et al., Notch signaling is a critical initiator of roof plate formation as revealed by the use of RNA profiling of the dorsal neural tube. BMC Biol. 2021 Apr 23;19(1):84
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7339068
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-cleaved Caspase-3 (Asp175; #9661)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen S10A: embryonic day 9.5 (more )
Note: Double labeled: red - Casp3; green - Tfap2a (assay MGI:7339066).
Structure Cell Type Level Pattern Image Note
TS15: migrating neural crest neural crest cell Absent S10A
TS15: neural tube neural crest cell Absent S10A
Specimen S10B: embryonic day 9.5; Mib1tm2Kong/Mib1tm2Kong, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. Double labeled: red - Casp3; green - Tfap2a (assay MGI:7339066).
Structure Cell Type Level Pattern Image Note
TS15: migrating neural crest neural crest cell Absent S10B Similar as in the wild-type.
TS15: neural tube neural crest cell Absent S10B Similar as in the wild-type.
Specimen S10C: embryonic day 10.5 (more )
Note: Double labeled: red - Casp3; green - Tfap2a (assay MGI:7339066).
Structure Level Pattern Image Note
TS17: dorsal root ganglion Absent S10C
TS17: neural tube Absent S10C
Specimen S10D: embryonic day 10.5; Mib1tm2Kong/Mib1tm2Kong, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. Double labeled: red - Casp3; green - Tfap2a (assay MGI:7339066).
Structure Level Pattern Image Note
TS17: dorsal root ganglion Absent S10D
TS17: neural tube Absent S10D
Specimen S10E: embryonic day 11.5 (more )
Note: Double labeled: red - Casp3; green - Tfap2a (assay MGI:7339066).
Structure Level Pattern Image Note
TS19: dorsal root ganglion Ambiguous S10E
Specimen S10F: embryonic day 11.5; Mib1tm2Kong/Mib1tm2Kong, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. Double labeled: red - Casp3; green - Tfap2a (assay MGI:7339066).
Structure Level Pattern Image Note
TS19: dorsal root ganglion Present S10F
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/15/2024
MGI 6.24 		The Jackson Laboratory