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Gene Expression Data
Assay Details
Assay
Reference: J:226322 Roux M, et al., Hoxb1 regulates proliferation and differentiation of second heart field progenitors in pharyngeal mesoderm and genetically interacts with Hoxa1 during cardiac outflow tract development. Dev Biol. 2015 Oct 15;406(2):247-58
Assay type: RNA in situ
MGI Accession ID: MGI:7345659
Gene symbol: Fgf8
Gene name: fibroblast growth factor 8
Probe: Fgf8 probe138
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: branchial arch endoderm Present Regionally restricted 2A Expressed in the lateral pharyngeal endoderm.
TS15: surface ectoderm Present 2A
TS15: branchial arch mesenchyme Weak Regionally restricted 2A Expressed in the lateral pharyngeal mesoderm.
Specimen 2B: embryonic day 9.5; Hoxb1tm5Mrc/Hoxb1tm5Mrc (more )
Structure Level Pattern Image Note
TS15: surface ectoderm Present 2B
TS15: branchial arch endoderm Present Regionally restricted 2B Expressed in the lateral pharyngeal endoderm.
TS15: branchial arch mesenchyme Present Regionally restricted 2B Abnormally expressed in ventral pharyngeal mesoderm in the dorsal pericardial wall.
Specimen 2C: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: surface ectoderm Present 2C
TS15: branchial arch endoderm Present Regionally restricted 2C Expressed in the lateral pharyngeal endoderm.
TS15: branchial arch mesenchyme Weak Regionally restricted 2C Expressed in the lateral pharyngeal mesoderm.
Specimen 2D: embryonic day 9.5; Hoxb1tm5Mrc/Hoxb1tm5Mrc (more )
Structure Level Pattern Image Note
TS15: surface ectoderm Present 2D
TS15: branchial arch endoderm Present Regionally restricted 2D Expressed in the lateral pharyngeal endoderm.
TS15: branchial arch mesenchyme Present Regionally restricted 2D Abnormally expressed in ventral pharyngeal mesoderm in the dorsal pericardial wall.
Specimen 4I: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: surface ectoderm Present 4I
TS15: branchial arch endoderm Present Regionally restricted 4I Expressed in the lateral pharyngeal endoderm.
TS15: branchial arch mesenchyme Present Regionally restricted 4I Expressed in the lateral pharyngeal mesoderm.
Specimen 4J: embryonic day 9.5; Hoxa1tm1Ipc/Hoxa1tm1Ipc (more )
Structure Level Pattern Image Note
TS15: surface ectoderm Present 4J Similar as in the wild-type.
TS15: branchial arch endoderm Present Regionally restricted 4J Expressed in the lateral pharyngeal endoderm, similar as in the wild-type.
TS15: branchial arch mesenchyme Present Regionally restricted 4J Expressed in the lateral pharyngeal mesoderm, similar as in the wild-type.
Specimen S7A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: branchial arch Present S7A
Specimen S7B: embryonic day 9.5; Hoxa1tm1Ipc/Hoxa1tm1Ipc (more )
Structure Level Pattern Image Note
TS15: branchial arch Present S7B Similar as in the wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory