Gene Expression Data
Assay Details
Assay
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Reference:
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J:309724
Rux D, et al., Hox11 expression characterizes developing zeugopod synovial joints and is coupled to postnatal articular cartilage morphogenesis into functional zones in mice. Dev Biol. 2021 Sep;477:49-63
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7378535
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Gene symbol:
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Hoxa11
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Gene name:
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homeobox A11
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Probe:
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Mm-Hoxa11 (495561)
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Probe preparation:
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Antisense
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Visualized with:
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Fluorescence
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Assay notes:
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RNAscope was performed using the RED2.5 detection system.
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Results
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Specimen
7A:
embryonic day 15.5
(more )
Specimen
7A:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 15.5
|
Sex:
|
Not Specified
|
Type:
|
section
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Fixation:
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4% Paraformaldehyde
|
Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS23: forelimb |
Present |
Regionally restricted |
7A
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High expression was noted in the distal zeugopod surrounding and including the developing distal growth plates. Highest expression was restricted to distal end of both zeugopod bones and most proximal wrist bones.
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TS23: zeugopod |
Present |
Regionally restricted |
7A
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High expression was noted in the distal zeugopod surrounding and including the developing distal growth plates. Highest expression was restricted to distal end of both zeugopod bones and most proximal wrist bones.
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TS23: scapholunate |
Present |
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7A
|
|
Specimen
7D:
postnatal newborn
(more )
Specimen
7D:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
postnatal newborn
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
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Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: wrist |
Present |
Widespread |
7D
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High expression was detected broadly in all elements of the newborn wrist.
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Specimen
7F:
postnatal newborn
(more )
Specimen
7F:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
postnatal newborn
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Specimen
7H:
postnatal month 2
(more )
Specimen
7H:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
postnatal month 2
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: wrist |
Present |
Regionally restricted |
7H
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Expression was maintained in wrist cartilage in the adult.
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Specimen
7J:
postnatal month 2
(more )
Specimen
7J:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
postnatal month 2
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: synovium |
Present |
Regionally restricted |
7J
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Expression was detected in the wrist synovium.
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Specimen
8A:
embryonic day 15.5
(more )
Specimen
8A:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 15.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Specimen
8D:
postnatal newborn
(more )
Specimen
8D:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
postnatal newborn
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Sex:
|
Not Specified
|
Type:
|
section
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Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
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Specimen
8G:
postnatal newborn
(more )
Note: medial region.
Specimen
8G:
(close )
Genetic Background:
|
Not Specified
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Age:
|
postnatal newborn
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Sex:
|
Not Specified
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Type:
|
section
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Fixation:
|
4% Paraformaldehyde
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Embedding:
|
Paraffin
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Note:
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medial region.
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Structure |
Level |
Pattern |
Image |
Note |
TS27: knee joint |
Present |
Regionally restricted |
8G Hoxa11
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High expression was detected in the medial region.
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Specimen
8H:
postnatal newborn
(more )
Note: center region.
Specimen
8H:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
postnatal newborn
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Note:
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center region.
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: knee joint |
Present |
Regionally restricted |
8H Hoxa11
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High expression was detected in the center region.
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Specimen
8I:
postnatal newborn
(more )
Note: lateral region.
Specimen
8I:
(close )
Genetic Background:
|
Not Specified
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Age:
|
postnatal newborn
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Sex:
|
Not Specified
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Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
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Note:
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lateral region.
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Specimen
8J:
postnatal newborn
(more )
Note: patella region.
Specimen
8J:
(close )
Genetic Background:
|
Not Specified
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Age:
|
postnatal newborn
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Sex:
|
Not Specified
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Type:
|
section
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Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
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Note:
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patella region.
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Specimen
8K:
postnatal month 2
(more )
Specimen
8K:
(close )
Genetic Background:
|
Not Specified
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Age:
|
postnatal month 2
|
Sex:
|
Not Specified
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Type:
|
section
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Fixation:
|
4% Paraformaldehyde
|
Embedding:
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Paraffin
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Specimen
8L:
postnatal month 2
(more )
Specimen
8L:
(close )
Genetic Background:
|
Not Specified
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Age:
|
postnatal month 2
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
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Specimen
8M:
postnatal month 2
(more )
Specimen
8M:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
postnatal month 2
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: knee joint |
Present |
Regionally restricted |
8M Hoxa11
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Expression was detected in cartilage.
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Specimen
8N:
postnatal month 2
(more )
Specimen
8N:
(close )
Genetic Background:
|
Not Specified
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Age:
|
postnatal month 2
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: ligament |
Present |
Regionally restricted |
8N Hoxa11
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Expression was detected in the knee ligament.
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Specimen
8O:
postnatal month 2
(more )
Specimen
8O:
(close )
Genetic Background:
|
Not Specified
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Age:
|
postnatal month 2
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Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: bone marrow |
Present |
Regionally restricted |
8O Hoxa11
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Expression was detected in the tibia bone marrow.
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Specimen
S5A:
embryonic day 15.5
(more )
Specimen
S5A:
(close )
Genetic Background:
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Not Specified
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Age:
|
embryonic day 15.5
|
Sex:
|
Not Specified
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Type:
|
section
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Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Specimen
S5D:
embryonic day 15.5
(more )
Specimen
S5D:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 15.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Specimen
S5G:
embryonic day 15.5
(more )
Specimen
S5G:
(close )
Genetic Background:
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Not Specified
|
Age:
|
embryonic day 15.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
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