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Gene Expression Data
Assay Details
Assay
Reference: J:158583 Ko HW, et al., Broad-minded links cell cycle-related kinase to cilia assembly and hedgehog signal transduction. Dev Cell. 2010 Feb 16;18(2):237-47
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7380671
Gene symbol: Pax6
Gene name: paired box 6
Antibody: anti-Pax6
Detection system: Secondary antibody
Assay notes: Two antibodies were described, but the one used in this assay was not detailed. Pax6 antibody MGI:7380627 may have been used in this assay.
Results
Specimen 1A Pax6 WT: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 1A Pax6 WT Expression in motoneuron domain.
Specimen 1A Pax6 bromi: embryonic day 10.5; Tbc1d32bromi/Tbc1d32bromi (more )
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 1A Pax6 bromi Expression ectopically expanded into more ventral regions.
Specimen 2 Pax6 WT: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: neural tube Present 2_Pax6 WT
Specimen 2 Pax6 bromi: embryonic day 9.5; Tbc1d32bromi/Tbc1d32bromi (more )
Structure Level Pattern Image Note
TS15: neural tube Present 2_Pax6 bromi
Specimen 2 Pax6 Ptch1: embryonic day 9.5; Ptch1tm1Mps/Ptch1tm1Mps (more )
Structure Level Pattern Image Note
TS15: neural tube Absent 2_Pax6 Ptch1
Specimen 2 Pax6 bromi,Ptch1: embryonic day 9.5; Ptch1tm1Mps/Ptch1tm1Mps, Tbc1d32bromi/Tbc1d32bromi (more )
Structure Level Pattern Image Note
TS15: neural tube Present 2_Pax6 bromi,Ptch1 Expression pattern similar to bromi single mutant.
Specimen S2A Pax6 WT: embryonic day 9.5 (more )
Note: Double labeled: red - Pax6; green - Nkx6-1 (assay MGI:7380673).
Structure Level Pattern Image Note
TS15: neural tube Present Regionally restricted S2A (upper) WT Expression in dorsal neural tube.
Specimen S2A Pax6 bromi: embryonic day 9.5; Tbc1d32bromi/Tbc1d32bromi (more )
Note: Double labeled: red - Pax6; green - Nkx6-1 (assay MGI:7380673).
Structure Level Pattern Image Note
TS15: neural tube Present Widespread S2A (upper) bromi Expression throughout neural tube.
Specimen S2A Pax6 Prch1: embryonic day 9.5; Ptch1tm1Mps/Ptch1tm1Mps (more )
Note: Double labeled: red - Pax6; green - Nkx6-1 (assay MGI:7380673).
Structure Level Pattern Image Note
TS15: neural tube Absent S2A (upper) Ptch1
Specimen S2A Pax6 bromi,Ptch1: embryonic day 9.5; Ptch1tm1Mps/Ptch1tm1Mps, Tbc1d32bromi/Tbc1d32bromi (more )
Note: Double labeled: red - Pax6; green - Nkx6-1 (assay MGI:7380673).
Structure Level Pattern Image Note
TS15: neural tube Present Widespread S2A (upper) bromi,Ptch1 Expression throughout neural tube. Dorsal border of expression expanded dorsally compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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