Nkx6-1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:158583 Ko HW, et al., Broad-minded links cell cycle-related kinase to cilia assembly and hedgehog signal transduction. Dev Cell. 2010 Feb 16;18(2):237-47
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7380673
Gene symbol:	Nkx6-1
Gene name:	NK6 homeobox 1

Antibody:	anti-Nkx6.1
Detection system:	Secondary antibody

Results

Specimen S2A Nkx6.1 WT: embryonic day 9.5 (more

)
Note: Double labeled: green - Nkx6-1; red - Pax6 (assay MGI:7380671).

Structure	Level	Pattern	Image	Note
TS15: neural tube	Present	Regionally restricted	S2A (upper) WT	Expression in ventral neural tube.

Specimen S2A Nkx6.1 bromi: embryonic day 9.5; Tbc1d32^bromi/Tbc1d32^bromi (more

)
Note: Double labeled: green - Nkx6-1; red - Pax6 (assay MGI:7380671).

Structure	Level	Pattern	Image	Note
TS15: neural tube	Present	Regionally restricted	S2A (upper) bromi	Expression in ventral neural tube.

Specimen S2A Nkx6.1 Ptch1: embryonic day 9.5 (more

)
Note: Double labeled: green - Nkx6-1; red - Pax6 (assay MGI:7380671).

Structure	Level	Pattern	Image	Note
TS15: neural tube	Present	Regionally restricted	S2A (upper) Ptch1

Specimen S2A Nkx6.1 bromi,Ptch1: embryonic day 9.5; Ptch1^tm1Mps/Ptch1^tm1Mps, Tbc1d32^bromi/Tbc1d32^bromi (more

)
Note: Double labeled: green - Nkx6-1; red - Pax6 (assay MGI:7380671).

Structure	Level	Pattern	Image	Note
TS15: neural tube	Present	Regionally restricted	S2A (upper) bromi,Ptch1	Dorsal border of expression shited compared to wild type.

Specimen S2C Nkx6.1 WT: embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: neural tube	Present	Regionally restricted	S2C Nkx6.1 WT	Expression in ventral neural tube.

Specimen S2C Nkx6.1 bromi: embryonic day 10.5; Tbc1d32^bromi/Tbc1d32^bromi (more

)

Structure	Level	Pattern	Image	Note
TS17: neural tube	Present	Regionally restricted	S2C Nkx6.1 bromi

Specimen S2C Nkx6.1 Rab23opb2: embryonic day 10.5; Rab23^opb2/Rab23^opb2 (more

)

Structure	Level	Pattern	Image	Note
TS17: neural tube	Present	Regionally restricted	S2C Nkx6.1 Rab23opb2	Expression domain shifted compared to wild type.

Specimen S2C Nkx6.1 bromi,Rab23opb2: embryonic day 10.5; Rab23^opb2/Rab23^opb2, Tbc1d32^bromi/Tbc1d32^bromi (more

)

Structure	Level	Pattern	Image	Note
TS17: neural tube	Present	Regionally restricted	S2C Nkx6.1 bromi,Rab23opb2	Authors report same dorsalized phenotype as in bromi single mutants.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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