About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:328556 Sunny SS, et al., Multiple roles of Pax6 in postnatal cornea development. Dev Biol. 2022 Aug 29;491:1-12
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7397277
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-caspase 3
Detection system: Secondary antibody
Assay notes: This antibody recognizes the cleaved form of the protein.
Results
Specimen S4A: postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: red - Casp3; green - Pax6 (assay MGI:7397248).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Single cells S4A

Specimen S4A': postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant. Double labeled: red - Casp3; green - Pax6 (assay MGI:7397248).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Single cells S4A' There was no significant difference in the number of positive cells between wild type and this mutant.

Specimen S4B: postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: red - Casp3; green - Pax6 (assay MGI:7397248).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Single cells S4B

Specimen S4B': postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant. Double labeled: red - Casp3; green - Pax6 (assay MGI:7397248).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Single cells S4B' There was no significant difference in the number of positive cells between wild type and this mutant.

Specimen S4C: postnatal day 28; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: red - Casp3; green - Pax6 (assay MGI:7397248).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Single cells S4C

Specimen S4C': postnatal day 28; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant. Double labeled: red - Casp3; green - Pax6 (assay MGI:7397248).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Single cells S4C' There was no significant difference in the number of positive cells between wild type and this mutant.

Specimen S4D: postnatal day 28; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: red - Casp3; green - Pax6 (assay MGI:7397248).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Single cells S4D

Specimen S4D': postnatal day 28; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant. Double labeled: red - Casp3; green - Pax6 (assay MGI:7397248).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Single cells S4D' There was no significant difference in the number of positive cells between wild type and this mutant.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
09/17/2024
MGI 6.24
The Jackson Laboratory