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Gene Expression Data
Assay Details
Assay
Reference: J:225376 Okada K, et al., Identification of SCAN domain zinc-finger gene ZNF449 as a novel factor of chondrogenesis. PLoS One. 2014;9(12):e115169
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7413896
Gene symbol: Zfp449
Gene name: zinc finger protein 449
Antibody: anti-ZNF449
Results
Specimen 2B: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: cartilage periarticular chondrocyte Present 2B top , 2B Zfp449 Pro Merge , 2B Zfp449 Per Merge , 2B Zfp449 Hyp , 2B Zfp449 Per , 2B Zfp449 Hyp Merge , 2B Zfp449 Pro Expression is in the nuclei of periarticular zone, proliferative zone, and hypertrophic zone and decreased in accordance with differentiation.
TS26: tibia periarticular chondrocyte Present 2B top , 2B Zfp449 Pro Merge , 2B Zfp449 Per Merge , 2B Zfp449 Hyp , 2B Zfp449 Per , 2B Zfp449 Hyp Merge , 2B Zfp449 Pro Expression is in the nuclei of periarticular zone, proliferative zone, and hypertrophic zone and decreased in accordance with differentiation.

Specimen 2C: postnatal week 8 (more )
Structure Cell Type Level Pattern Image Note
TS28: articular cartilage articular chondrocyte Present 2C top , 2C Merge , 2C bottom left Expression is in the nuclei of chondrocytes.
TS28: knee joint articular chondrocyte Present 2C top , 2C Merge , 2C bottom left Expression is in the nuclei of chondrocytes.

Specimen 5A +/+: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cartilage Present 5A Zfp449 +/+
TS26: tibia Present 5A Zfp449 +/+

Specimen 5A -/-: embryonic day 18.5; Zfp449tm1Taks/Zfp449tm1Taks (more )
Structure Level Pattern Image Note
TS26: cartilage Absent 5A Zfp449 -/-
TS26: tibia Absent 5A Zfp449 -/-

Specimen 5E Zfp449: postnatal; Zfp449tm1Taks/Zfp449+ (more )
Structure Level Pattern Image Note
TS28: elbow joint Present 5E Zfp449


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/17/2024
MGI 6.24
The Jackson Laboratory