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Gene Expression Data
Assay Details
Assay
Reference: J:332131 Perera SN, et al., Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584
Assay type: RNA in situ
MGI Accession ID: MGI:7425003
Gene symbol: Alx3
Gene name: aristaless-like homeobox 3
Probe: Alx3 cDNA5
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 7 - Alx3: embryonic day 16.5 (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Schwann cells and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer olfactory ensheathing cell Present Non-Uniform 7s , 7r The outer ONL-OECs show stronger expression than the inner ones.
TS24: olfactory nerve olfactory ensheathing cell Present 7r , 7t The mucosal OECs show expression, more strongly than the inner ONL-OECs.
TS24: trigeminal nerve Schwann cell Absent 7r , 7u The Schwann cells lack expression.
Specimen 9 - E11.5: embryonic day 11.5 (more )
Note: Parasagittal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Schwann cells and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS20: olfactory nerve olfactory ensheathing cell Present 9n , 9o The mucosal OECs show expression.
TS20: head mesenchyme Strong Regionally restricted 9n , 9o Strong expression is seen in frontonasal mesenchyme cells, subadjacent to the olfactory epithelium.
Specimen 9 - E13 - p1: embryonic day 13.0 (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Schwann cells and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS21: main olfactory bulb layer olfactory ensheathing cell Present 9q1 , 9p1 The olfactory nerve layer OECs show expression.
Specimen 9 - E13 - p2: embryonic day 13.0 (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Schwann cells and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS21: olfactory nerve olfactory ensheathing cell Present 9q2 , 9p2 The mucosal OECs show expression.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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08/21/2024
MGI 6.24 		The Jackson Laboratory