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Gene Expression Data
Assay Details
Assay
Reference: J:320419 Li R, et al., E3 ubiquitin ligase FBXW7 balances airway cell fates. Dev Biol. 2022 Mar;483:89-97
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7427629
Gene symbol: Muc5ac
Gene name: mucin 5, subtypes A and C, tracheobronchial/gastric
Antibody: anti-MUC5AC (45M1)
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 2D: embryonic day 18.5; Fbxw7tm1Iaai/Fbxw7+, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: trachea epithelium tracheal goblet cell Absent 2D A rare cell type in the control.
Specimen 2E: embryonic day 18.5; Fbxw7tm1Iaai/Fbxw7tm1Iaai, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: trachea epithelium tracheal goblet cell Present 2E There was a prominent increase of positive cells compared with the control.
Specimen 4D: embryonic day 18.5; Fbxw7tm1Iaai/Fbxw7+, Notch1tm1Agt/Notch1+, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: trachea epithelium tracheal goblet cell Absent 4D A rare cell type in the control.
Specimen 4E: embryonic day 18.5; Fbxw7tm1Iaai/Fbxw7tm1Iaai, Notch1tm1Agt/Notch1+, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: trachea epithelium tracheal goblet cell Present 4E There was a prominent increase of positive cells compared with the control.
Specimen 4F: embryonic day 18.5; Fbxw7tm1Iaai/Fbxw7tm1Iaai, Notch1tm1Agt/Notch1tm1Agt, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: trachea epithelium tracheal goblet cell Present 4F Increased expression persisted.
Specimen 5D: embryonic day 18.5; Fbxw7tm1Iaai/Fbxw7+, Klf5tm1Jaw/Klf5+, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: trachea epithelium tracheal goblet cell Absent 5D A rare cell type in the control.
Specimen 5E: embryonic day 18.5; Fbxw7tm1Iaai/Fbxw7tm1Iaai, Klf5tm1Jaw/Klf5+, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: trachea epithelium tracheal goblet cell Present 5E There was a prominent increase of positive cells compared with the control.
Specimen 5F: embryonic day 18.5; Fbxw7tm1Iaai/Fbxw7tm1Iaai, Klf5tm1Jaw/Klf5tm1Jaw, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: trachea epithelium tracheal goblet cell Absent 5F No increase of positive cells compared with the control.
Specimen S5C: embryonic day 18.5; Fbxw7tm1Iaai/Fbxw7+, Notch1tm1Agt/Notch1+, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: trachea epithelium tracheal goblet cell Absent S5C A rare cell type in the control.
Specimen S5D: embryonic day 18.5; Fbxw7tm1Iaai/Fbxw7+, Notch1tm1Agt/Notch1tm1Agt, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: trachea epithelium tracheal goblet cell Absent S5D Similar as in the control.
Specimen S6C: embryonic day 18.5; Fbxw7tm1Iaai/Fbxw7+, Klf5tm1Jaw/Klf5+, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: trachea epithelium tracheal goblet cell Absent S6C
Specimen S6D: embryonic day 18.5; Fbxw7tm1Iaai/Fbxw7+, Klf5tm1Jaw/Klf5tm1Jaw, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: trachea epithelium tracheal goblet cell Absent S6D Similar as in the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/17/2024
MGI 6.24 		The Jackson Laboratory