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Gene Expression Data
Assay Details
Assay
Reference: J:320419 Li R, et al., E3 ubiquitin ligase FBXW7 balances airway cell fates. Dev Biol. 2022 Mar;483:89-97
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7427654
Gene symbol: Hes1
Gene name: hes family bHLH transcription factor 1
Antibody: anti-HES1 (PA5-28802)
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 4J: embryonic day 18.5; Fbxw7tm1Iaai/Fbxw7+, Notch1tm1Agt/Notch1+, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: trachea Present 4J

Specimen 4K: embryonic day 18.5; Fbxw7tm1Iaai/Fbxw7tm1Iaai, Notch1tm1Agt/Notch1+, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: trachea Present 4K Increased expression compared with the control.

Specimen 4L: embryonic day 18.5; Fbxw7tm1Iaai/Fbxw7tm1Iaai, Notch1tm1Agt/Notch1tm1Agt, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: trachea Present 4L Reduced expression compared to Shhcre/+;Fbxw7f/f;Notch1f/+ trachea.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/17/2024
MGI 6.24
The Jackson Laboratory