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Gene Expression Data
Assay Details
Assay
Reference: J:209131 Saba R, et al., CYP26B1 promotes male germ cell differentiation by suppressing STRA8-dependent meiotic and STRA8-independent mitotic pathways. Dev Biol. 2014 May 15;389(2):173-81
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7428654
Gene symbol: Dnmt3l
Gene name: DNA methyltransferase 3-like
Antibody: anti-DNMT3L
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2D: embryonic day 16.5; Cyp26b1tm1Hmd/Cyp26b1+, Stra8tm1Ysa/Stra8+ (more )
Note: Data was quantified in Fig 2H. Double labeled: green - Dnmt3l; magenta - Gcna (assay MGI:7428651).
Structure Level Pattern Image Note
TS24: germ cell of testis Present Widespread 2D Expressed in all germ cells.
Specimen 2E: embryonic day 16.5; Cyp26b1tm1Hmd/Cyp26b1tm1Hmd, Stra8tm1Ysa/Stra8+ (more )
Note: Data was quantified in Fig 2H. Double labeled: green - Dnmt3l; magenta - Gcna (assay MGI:7428651).
Structure Level Pattern Image Note
TS24: germ cell of testis Trace 2E Expression was completely suppressed in germ cells.
Specimen 2F: embryonic day 16.5; Cyp26b1tm1Hmd/Cyp26b1tm1Hmd, Stra8tm1Ysa/Stra8tm1Ysa (more )
Note: Data was quantified in Fig 2H. Double labeled: green - Dnmt3l; magenta - Gcna (assay MGI:7428651).
Structure Level Pattern Image Note
TS24: germ cell of testis Present 2F Only expressed in some of the germ cells (about 50%).
Specimen S2F: embryonic day 14.5; Cyp26b1tm1Hmd/Cyp26b1+, Stra8tm1Ysa/Stra8+ (more )
Note: Double labeled: green - Dnmt3l; magenta - Gcna (assay MGI:7428651).
Structure Level Pattern Image Note
TS22: germ cell of testis Present Widespread S2F Expressed in almost all germ cells.
Specimen S2G: embryonic day 14.5; Cyp26b1tm1Hmd/Cyp26b1tm1Hmd, Stra8tm1Ysa/Stra8+ (more )
Note: Double labeled: green - Dnmt3l; magenta - Gcna (assay MGI:7428651).
Structure Level Pattern Image Note
TS22: germ cell of testis Absent S2G
Specimen S2H: embryonic day 14.5; Cyp26b1tm1Hmd/Cyp26b1tm1Hmd, Stra8tm1Ysa/Stra8tm1Ysa (more )
Note: Double labeled: green - Dnmt3l; magenta - Gcna (assay MGI:7428651).
Structure Level Pattern Image Note
TS22: germ cell of testis Absent S2H
Specimen S2I: embryonic day 18.5; Cyp26b1tm1Hmd/Cyp26b1+, Stra8tm1Ysa/Stra8+ (more )
Note: Data was quantified in Fig 2H. Double labeled: green - Dnmt3l; magenta - Gcna (assay MGI:7428651).
Structure Level Pattern Image Note
TS26: germ cell of testis Present Widespread S2I Expressed in almost all germ cells.
Specimen S2J: embryonic day 18.5; Cyp26b1tm1Hmd/Cyp26b1tm1Hmd, Stra8tm1Ysa/Stra8tm1Ysa (more )
Note: Data was quantified in Fig 2H. Double labeled: green - Dnmt3l; magenta - Gcna (assay MGI:7428651).
Structure Level Pattern Image Note
TS26: germ cell of testis Present S2J Only expressed in some of the germ cells.
Specimen not shown: embryonic day 16.5; Cyp26b1tm1Hmd/Cyp26b1tm1Hmd, Stra8tm1Ysa/Stra8tm1Ysa (more )
Structure Level Pattern Image Note
TS24: germ cell of testis Present Expressed in some of the germ cells (about 50%).
Specimen not shown: embryonic day 16.5; Cyp26b1tm1Hmd/Cyp26b1tm1Hmd, Nanos2tm1Ysa/Nanos2tm1Ysa, Stra8tm1Ysa/Stra8tm1Ysa (more )
Structure Level Pattern Image Note
TS24: germ cell of testis Absent
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/09/2024
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