Notch1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:229936 Cano E, et al., Extracardiac septum transversum/proepicardial endothelial cells pattern embryonic coronary arterio-venous connections. Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):656-61
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7431190
Gene symbol:	Notch1
Gene name:	notch 1

Antibody:	anti-cleaved Notch1 (Val1744) antibody (anti-NICD) (#2421)
Detection system:	Secondary antibody

Results

3C ©

Specimen 3C: embryonic day 16.5; Wt1^tm1.1Ndha/Wt1^tm1.1Ndha (more

)
Note: Double labeled: red - Notch1; green - IB4 staining.

Structure	Cell Type	Level	Pattern	Image	Note
TS24: coronary artery	endothelial cell of coronary artery	Present		3C

3F ©

Specimen 3F: embryonic day 16.5; Wt1^tm1.1Ndha/Wt1^tm1.1Ndha, Tg(Gata4*G2-cre)#Roja/0 (more

)
Note: Conditional mutant. Double labeled: red - Notch1; green - IB4 staining.

Structure	Level	Pattern	Image	Note
TS24: heart blood vessel	Present		3F	Mutant blood vessels did not form normal transmural coronary blood vessels, failing to connect to the deeper vascular elements of the developing coronary vasculature.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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