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Gene Expression Data
Assay Details
Assay
Reference: J:325730 Ahuja N, et al., Endothelial Cyp26b1 restrains murine heart valve growth during development. Dev Biol. 2022 Jun;486:81-95
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7444030
Gene symbol: Pbx1
Gene name: pre B cell leukemia homeobox 1
Antibody: anti-Pbx1 (4342)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 6A: embryonic day 15.5 (more )
Note: Triple labeled: green - Pbx1; white - Sox9 (assay MGI:7444046); red - Nfatc1 (assay MGI:7444038).
Structure Level Pattern Image Note
TS23: semilunar valve Ambiguous 6A , 6A'
Specimen 6B: embryonic day 15.5; Cyp26b1em1Oncl/Cyp26b1em1Oncl (more )
Note: Triple labeled: green - Pbx1; white - Sox9 (assay MGI:7444046); red - Nfatc1 (assay MGI:7444038).
Structure Level Pattern Image Note
TS23: semilunar valve Present Regionally restricted 6B' , 6B There was a broad increase in immunoreactivity in the mutant semilunar valve endothelium and mesenchyme.
TS23: heart Present Regionally restricted 6B , 6B' Immunoreactivity was increased in the aortic root surrounding the semilunar valve in the mutant.
Specimen S7A: embryonic day 15.5 (more )
Note: Triple labeled: green - Pbx1; white - Sox9 (assay MGI:7444046); red - Nfatc1 (assay MGI:7444038).
Structure Level Pattern Image Note
TS23: aortic valve Present S7A' , S7A
Specimen S7B: embryonic day 15.5; Cyp26b1em1Oncl/Cyp26b1em1Oncl (more )
Note: Triple labeled: green - Pbx1; white - Sox9 (assay MGI:7444046); red - Nfatc1 (assay MGI:7444038).
Structure Level Pattern Image Note
TS23: aortic valve Present S7B' , S7B Expression was dramatically increased in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/17/2024
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