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Gene Expression Data
Assay Details
Assay
Reference: J:325730 Ahuja N, et al., Endothelial Cyp26b1 restrains murine heart valve growth during development. Dev Biol. 2022 Jun;486:81-95
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7444320
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-cleaved Caspase-3 (Asp175; #9661)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen S6C: embryonic day 18.5 (more )
Note: Double labeled: green - Casp3; white - Tnnt2 (assay MGI:7444020).
Structure Level Pattern Image Note
TS26: aortic valve leaflet Present Single cells S6C

Specimen S6D: embryonic day 18.5; Cyp26b1em1Oncl/Cyp26b1em1Oncl (more )
Note: Double labeled: green - Casp3; white - Tnnt2 (assay MGI:7444020).
Structure Level Pattern Image Note
TS26: aortic valve leaflet Present Single cells S6D There was no change in cleaved-Casp3 immunopositive cells in the aortic valve leaflets in the mutant compared with wild type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/17/2024
MGI 6.24
The Jackson Laboratory